Results 311 to 320 of about 213,935 (349)

Insulin and epidermal growth factor stimulate poly ADP-ribosylation

Biochemical and Biophysical Research Communications, 1981
Abstract Treatment of contact-inhibited BALBc 3T3 fibroblasts with insulin or epidermal growth factor elicited a considerable increase in the capacity of poly (ADP-ribose) synthesis. Stimulation of the poly ADP-ribosylation was observed after long-term hormone treatment (18 hours) but not after short-term treatment (1 hour) and it appeared to ...
Shimizu, Y, Shimizu, N
openaire   +3 more sources

Structure of the human ADP-ribosylation factor 1 complexed with GDP

Nature, 1994
ADP-ribosylation factors (ARFs) are essential and ubiquitous in eukaryotes, being involved in vesicular transport and functioning as an activator of phospholipase D (refs 1, 2) and cholera toxin. The functions of ARF proteins in membrane traffic and organelle integrity are intimately tied to its reversible association with membranes and specific ...
David H. Harrison, Richard A. Kahn, Juan Carlos Amor, Dagmar Ringe   +3 more
openaire   +3 more sources

Endogenous ADP-ribosylation of elongation factor-2 by interleukin-1β

Molecular and Cellular Biochemistry, 2010
Eukaryotic elongation factor-2 (eEF-2) catalyses the motion of the growing peptide chain relative to the mRNA at the ribosomes during protein synthesis. This highly conserved G-protein is the specific target of two lethal bacterial toxins, Pseudomonas aeruginosa exotoxin A and diphtheria toxin.
Ursula Müller-Werdan, Karl Werdan, Doris Jäger   +2 more
openaire   +3 more sources

Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors.

Biochemical and Biophysical Research Communications - BBRC, 2000
We have cloned the cDNA encoding human PICK1 (protein interacting with C kinase 1), a PDZ domain-containing protein of 415 amino acids, and also identified the Drosophila homologue by search of the databank.
R. Takeya, K. Takeshige, H. Sumimoto
semanticscholar   +1 more source

Cloning and characterization of the human ADP-ribosylation factor 4 gene

Gene, 1999
ADP-ribosylation factor 4 (ARF4) is a member of a family of approximately 20 kDa guanine nucleotide-binding proteins that were initially identified by their ability to stimulate the ADP-ribosyltransferase activity of cholera toxin in vitro. They have recently been shown to play a role in vesicular trafficking and as activators of phospholipase D.
Ray A. Lebeda, Randy S. Haun
openaire   +3 more sources

Cloning of a carrot cDNA for a member of the family of ADP-ribosylation factors (ARFs) and characterization of the binding of nucleotides by its product after expression in E. coli.

Plant and Cell Physiology, 1995
A cDNA clone, designated DcArf1, was isolated from a cDNA library prepared from embryogenic cell clusters of Daucus carota and characterized. The cDNA (883 bp) contained an open reading frame that encoded a protein of 181 amino acid residues with ...
T. Kiyosue, K. Shinozaki
semanticscholar   +1 more source

Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1.

Biochemical and Biophysical Research Communications - BBRC, 2001
We first identified arfaptin as a protein that bound to GTP-ARFs (especially ARF1). However, a second group reported that POR1, a truncated form of arfaptin, bound to GTP-Rac1.
Ok Ho Shin, J. Exton
semanticscholar   +1 more source

Arfophilin is a common target of both class II and class III ADP-ribosylation factors.

Biochemistry, 2001
Arfophilin was first identified as a target protein for GTP-ARF5. The N-terminus of ARF5 (amino acids 2-17), which is distinct from that of class I or class III ARFs, is essential for binding to the C-terminus of arfophilin (amino acids 612-756).
O. Shin, A. Couvillon, J. Exton
semanticscholar   +1 more source

Growth factors mobilize multiple pools of KCa channels in developing parasympathetic neurons: role of ADP-ribosylation factors and related proteins.

Journal of Neurophysiology, 2005
In developing ciliary ganglion (CG) neurons, movement of functional large-conductance (BK type) Ca(2+)-activated K+ (K(Ca)) channels to the cell surface is stimulated by the endogenous growth factors TGF(beta)1 and beta-neuregulin-1 (NRG1).
K. Chae, K. Oh, S. Dryer
semanticscholar   +1 more source

Distribution of ADP-ribosylation factor-related protein 1 in mouse brain.

Archives italiennes de biologie, 2008
ADP-ribosylation factor (Arf)-related protein 1 (ARFRP1) is a membrane-associated GTPase, which inhibits the Arf/Sec7-dependent activation of phospholipase D and belongs to the Arf-like (Arl) GTPases. Although ARFRP1 is involved in post-Golgi membrane trafficking and its lack leads to embryonic lethality, little is known about its possible function in ...
Paratore S, Parenti R, Cavallaro S
openaire   +6 more sources