Results 141 to 150 of about 7,274 (190)

Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis. [PDF]

NAR Cancer
Ibrahim M, Roos WP, Schwartz JC, Khan MM, Al-Rahahleh RQ, Beers LA, Pearson CR, Langham KT, Boyang L, Clark J, Hayat F, Fang Q, Koczor CA, Migaud ME, Sobol RW.   +14 more
europepmc   +1 more source

Family-wide analysis of human macrodomains reveals novel activities and identifies PARG as most efficient ADPr-RNA hydrolase. [PDF]

Commun Biol
Weixler L, Žaja R, Ikenga NJ, Siefert J, Mohan G, Aydin G, Wijngaarden S, Filippov DV, Lüscher B, Feijs-Žaja KLH.   +9 more
europepmc   +1 more source

Ecto-ADP-ribose Transferases: Cell-Surface Response to Local Tissue Injury

Physiology, 2005
Ecto-ADP-ribose transferases (ecto-ARTs) catalyze the transfer of ADP-ribose from NAD+to arginine residues in cell-surface proteins. Since the concentration of extracellular NAD+is very low under normal physiological conditions but rises significantly upon tissue injury or membrane stress, it is postulated that the main role of ecto-ARTs is to ADP ...
Anna Zolkiewska
exaly   +4 more sources

Intrinsic ADP-Ribose Transferase Activity versus Levels of Mono(ADP-Ribose)Protein Conjugates in Proliferating Ehrlich Ascites Tumor Cells

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1979
Transition of proliferating Ehrlich ascites tumor cells (3 days after transplantation) to the non-proliferating status (8--14 days after transplantation) was associated with an increase in total mono (ADP-ribose) protein conjugates. This increase was largely confined to the NH2OH-resistant subfraction.
Reinhard Bredehorst, Markus GOEBEL, Fatma RENZI, M Kittler, Karin Klapproth, Helmuth Hilz   +5 more
openalex   +3 more sources

ADP-Ribosylation of Neurofilaments by a Cytoplasmic ADP-Ribose Transferase Associated with Free mRNP

Biochemical and Biophysical Research Communications, 1993
ADP-ribosylation of neurofilaments by an ADP-ribose transferase isolated from cytoplasmic ribonucleoprotein particles is demonstrated. The 150 kDa neurofilament subunit appears to be the main ADP-ribose acceptor with the transfer of ADP-ribose dimers or monomers.
M. Jesser, F. Hog, C. Chypre, J.F. Leterrier, P. Mandel   +4 more
openalex   +3 more sources

Speculations on the Roles of ADP-ribosyl Transferase Based on Analogies Between RecA and Poly(ADP-ribose) Polymerase

Journal of Theoretical Biology, 1993
A model for eukaryotic DNA damage repair is proposed in which poly(ADP-ribose) polymerase(NAD+ ADP-ribosyl transferase, EC 2,4,2,30) plays an important role. In this model, poly(ADP-ribose) polymerase regulates transcription of genes that are induced by DNA-damaging agents.
Joji Matsumoto
openalex   +3 more sources

Loss of poly(ADP-ribose) synthetase activity without change in arginine-specific ADP-ribosyltransferase activity by acid-treatment; application of the treatment to simple assay for transferase in the presence of poly(ADP-ribose) synthetase

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1993
We investigated the effects of acid treatment (pH 3.5) on the activities of arginine-specific ADP-ribosyltransferase (mono(ADP-ribosyl)transferase) (EC 2.4.2.31) and poly(ADP-ribose) synthetase (EC 2.4.2.30) purified from chicken liver, and we observed that the former enzyme retained completely its activity while there was no evidence for activity of ...
Shusaku Doi, Yoshinori Tanigawa, Mikako Tsuchiya, Makoto Shimoyama   +3 more
openalex   +3 more sources

Poly(ADP-Ribose) Transferase in Lizard Oviduct

, 1989
Poly(ADP-ribose) transferase often undergoes a drastic change in its activity following the action of various biological effectors in a variety of cell systems or tissues. An increase in poly(ADP-ribose) transferase activity was usually observed in those systems in which the biological effectors were followed with cell proliferation, for instance, in ...
Gaetano Ciarcia, Hisanori Suzuki, Massimo Lancieri   +2 more
openalex   +2 more sources