Results 21 to 30 of about 851 (142)

Myocardial mitochondrial and contractile function are preserved in mice lacking adiponectin. [PDF]

PLoS ONE, 2015
Adiponectin deficiency leads to increased myocardial infarct size following ischemia reperfusion and to exaggerated cardiac hypertrophy following pressure overload, entities that are causally linked to mitochondrial dysfunction.
Martin Braun, Niko Hettinger, Christoph Koentges, Katharina Pfeil, Maria C Cimolai, Michael M Hoffmann, Moritz Osterholt, Torsten Doenst, Christoph Bode, Heiko Bugger   +9 more
doaj   +1 more source

GsαR201C and estrogen reveal different subsets of bone marrow adiponectin expressing osteogenic cells

Bone Research, 2022
The Gsα/cAMP signaling pathway mediates the effect of a variety of hormones and factors that regulate the homeostasis of the post-natal skeleton. Hence, the dysregulated activity of Gsα due to gain-of-function mutations (R201C/R201H) results in severe ...
Biagio Palmisano, Rossella Labella, Samantha Donsante, Cristina Remoli, Emanuela Spica, Ilenia Coletta, Giorgia Farinacci, Michele Dello Spedale Venti, Isabella Saggio, Marta Serafini, Pamela Gehron Robey, Alessandro Corsi, Mara Riminucci   +12 more
doaj   +1 more source

Effects of Maternal Nutrient Restriction and Melatonin Supplementation on Cardiomyocyte Cell Development Parameters Using Machine Learning Techniques

Animals, 2022
The objective of the current study was to examine the effects of maternal feed restriction and melatonin supplementation on fetal cardiomyocyte cell development parameters and predict binucleation and hypertrophy using machine learning techniques using ...
Mitra Mazinani, Zully E. Contreras-Correa, Vahid Behzadan, Shreya Gopal, Caleb O. Lemley   +4 more
doaj   +1 more source

Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration

Cell Communication and Signaling, 2021
Background Metastasis represents the leading cause of death in patients with breast cancer. Traditional Chinese medicine is particularly appreciated for metastatic diseases in Asian countries due to its benefits for survival period prolongation and ...
Jing Li, Shengqi Wang, Neng Wang, Yifeng Zheng, Bowen Yang, Xuan Wang, Juping Zhang, Bo Pan, Zhiyu Wang   +8 more
doaj   +1 more source

ADQE: Obtain Better Deep Learning Models by Evaluating the Augmented Data Quality Using Information Entropy

Electronics, 2023
Data augmentation, as a common technique in deep learning training, is primarily used to mitigate overfitting problems, especially with small-scale datasets. However, it is difficult for us to evaluate whether the augmented dataset truly benefits the performance of the model.
Xiaohui Cui, Yu Li, Zheng Xie, Hanzhang Liu, Shijie Yang, Chao Mou   +5 more
openaire   +1 more source

A Deep Reinforcement Learning-Based Two-Dimensional Resource Allocation Technique for V2I Communications

IEEE Access, 2023
This paper proposes a two-dimensional resource allocation technique for vehicle-to-infrastructure (V2I) communications. Vehicular communications requires high data rates, low latency, and reliability simultaneously. The 3rd generation partnership project
Heetae Jin, Jeongbin Seo, Jeonghun Park, Suk Chan Kim   +3 more
doaj   +1 more source

Network Pharmacology-Based Validation of Caveolin-1 as a Key Mediator of Ai Du Qing Inhibition of Drug Resistance in Breast Cancer

Frontiers in Pharmacology, 2018
Chinese formulas have been paid increasing attention in cancer multidisciplinary therapy due to their multi-targets and multi-substances property.
Neng Wang, Bowen Yang, Bowen Yang, Xiaotong Zhang, Shengqi Wang, Shengqi Wang, Yifeng Zheng, Yifeng Zheng, Xiong Li, Xiong Li, Shan Liu, Hao Pan, Yingwei Li, Yingwei Li, Zhujuan Huang, Fengxue Zhang, Zhiyu Wang, Zhiyu Wang   +17 more
doaj   +1 more source

Dietary melatonin supplementation alters uteroplacental amino acid flux during intrauterine growth restriction in ewes

Animal, 2013
Dietary melatonin supplementation during mid- to late-gestation increased umbilical artery blood flow and caused disproportionate fetal growth. This melatonin-induced increase in umbilical artery blood flow may alter nutrient availability to the fetus ...
C.O. Lemley, L.E. Camacho, A.M. Meyer, M. Kapphahn, J.S. Caton, K.A. Vonnahme   +5 more
doaj   +1 more source

Types of Anxiety and Depression: Theoretical Assumptions and Development of the Anxiety and Depression Questionnaire

Frontiers in Psychology, 2018
The present paper is addressed to (1) the validation of a recently proposed typology of anxiety and depression, and (2) the presentation of a new tool—the Anxiety and Depression Questionnaire (ADQ)—based on this typology.
Małgorzata Fajkowska, Ewa Domaradzka, Agata Wytykowska   +2 more
doaj   +1 more source

Autonomic Dysfunctions in Parkinsonian Disorders [PDF]

Journal of Movement Disorders, 2009
Background and Purpose: Symptoms of autonomic dysfunctions are common in the patients with parkinsonian disorders. Because clinical features of autonomic dysfunctions are diverse, the comprehensive evaluation is essential for the appropriate management ...
Hyo-Jin Bae, Sang-Myung Cheon, Jae Woo Kim   +2 more
doaj   +1 more source