Results 101 to 110 of about 17,483 (252)

Practice-centred approach to research in design [PDF]

, 2000
This paper gives an overview of practice-centred research programmes at Sheffield Hallam University and discusses the principles behind practice-centred research, its place in the Design School, its effect on the regional economy and the community and ...
Chamberlain, C., Roddis, J., Rust, C.
core  

Analyses of plasma multi‐omic data across ancestries identify novel pathways implicated in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Few genetic studies on Alzheimer's disease (AD) have incorporated multiple ancestries and omic datasets to pinpoint actionable AD risk effectors for each ancestry. METHODS Here, we first performed genetic colocalization between molecular phenotypes (proteomics and metabolomics) from two ancestral groups (European [EUR] and African
Chengran Yang, Jigyasha Timsina, Menghan Liu, John Budde, Pat Kohlfeld, William Brock, John C. Morris, David M. Holtzman, Yun Ju Sung, Carlos Cruchaga   +9 more
wiley   +1 more source

Path Following Control of Fully Actuated Autonomous Underwater Vehicle Based on LADRC

Polish Maritime Research, 2018
This paper presents an active disturbances rejecter controller (ADRC) for position and path following control of a fully actuated autonomous underwater vehicle (AUV).
Lamraoui Habib Choukri, Qidan Zhu
doaj   +1 more source

Falls predict faster progression to Alzheimer's dementia

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION In preclinical Alzheimer's disease (AD), amyloid accumulates in the brain while individuals remain cognitively unimpaired (Clinical Dementia Rating® [CDR] = 0). Differentiating trajectories of healthy aging and preclinical AD is challenging as both are associated with age‐related impairments (e.g., falls).
Audrey A. Keleman, Melody Li, Julie K. Wisch, Rebecca M. Bollinger, Melissa J. Krauss, Elizabeth A. Grant, Tammie L. S. Benzinger, Beau M. Ances, John C. Morris, Susan L. Stark   +9 more
wiley   +1 more source

Associations between accelerometer‐derived physical activity complexity, cognitive function, and plasma biomarkers of Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION While higher physical activity (PA) levels are linked to lower Alzheimer's disease (AD) risk, traditional PA measures overlook temporal activity patterns. METHODS We developed the activity complexity measure in 164 older adults (mean age = 65.3 years) who completed wrist‐worn accelerometry and neuropsychological tests.
Yurun Cai, Beth E. Snitz, Ann D. Cohen
wiley   +1 more source

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. [PDF]

, 2019
Parietal cortex RNA-sequencing (RNA-seq) data were generated from individuals with and without Alzheimer disease (AD; ncontrol = 13; nAD = 83) from the Knight Alzheimer Disease Research Center (Knight ADRC).
Bateman, Randall J, Budde, John P, Chhatwal, Jasmeer P, Cruchaga, Carlos, Del-Aguila, Jorge L, Dominantly Inherited Alzheimer Network (DIAN), Dube, Umber, Farias, Fabiana, Fernandez, Maria Victoria, Gentsch, Jen, Graff-Radford, Neill R, Harari, Oscar, Hsu, Simon, Ibanez, Laura, Jiang, Shan, Karch, Celeste M, Lee, Jae-Hong, Li, Zeran, Masters, Colin L, Morris, John C, Norton, Joanne, Salloway, Stephen, Wang, Fengxian   +22 more
core  

First Contact with ADRC

Abstract We strive to make the initial encounter with ADRC a smooth and pleasant experience for novices. Therefore, in this chapter, we will rely heavily on illustrative examples inspired by real plants. With such a “show, don’t tell” narration, we want to introduce the fundamental aspects of ADRC for some easily recognizable systems from ...
Gernot Herbst, Rafal Madonski
openaire   +1 more source

Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Automated cerebrospinal fluid (CSF) biomarker assays have largely replaced manual immunoassays for measuring amyloid pathology in CSF. We refitted and validated the ABIDE model, predicting progression from mild cognitive impairment (MCI) to dementia, with CSF measurements from the automated Elecsys platform.
Pieter J. van der Veere, Argonde C. van Harten, Ingrid S. van Maurik, Charlotte E. Teunissen, Frederik Barkhof, Stephanie J. B. Vos, Lutz Froelich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters, Eckart Rüther, Giovanni B. Frisoni, Luiza Spiru, Yvonne Freund‐Levi, Åsa K. Wallin, Harald Hampel, Magda Tsolaki, Iwona Kłoszewska, Patrizia Mecocci, Bruno Vellas, Simon Lovestone, Samantha Galluzzi, Sanna‐Kaisa Herukka, Isabel Santana, I. Baldeiras, Alexandre de Mendonca, Dina Silva, Gael Chetelat, Géraldine Poisnel, Pieter Jelle Visser, Sterling C. Johnson, Erik Stormrud, Oskar Hansson, Sebastian Palmqvist, Gerard Piñol‐Ripoll, for the Alzheimer's Disease Neuroimaging Initiative, Johannes Berkhof, Wiesje M. van der Flier   +38 more
wiley   +1 more source

Discrete-Time Linear ADRC

Abstract We have now reached an important milestone in the book, and with this chapter we are moving from the theoretical foundations of ADRC to its applications. Putting ADRC in practice will almost always be in the form of a software-based implementation, be it in embedded systems or on PLC.
Gernot Herbst, Rafal Madonski
openaire   +1 more source

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease

Annals of Neurology, Volume 99, Issue 2, Page 492-501, February 2026.
Objective Lewy body disease (LBD) is a complex neurodegenerative disorder characterized by the accumulation of misfolded α‐synuclein in the brain. Neuroinflammation has long been implicated in LBD pathogenesis, and recent genetic studies in Parkinson's disease (a clinical manifestation of LBD) have shown consistent association with the human leukocyte ...
Marios Gavrielatos, Michael G. Heckman, Alexandra I. Soto‐Beasley, Sophia G. Blumenfeld, Xu Hou, Shunsuke Koga, Melissa E. Murray, Koji Kasanuki, Daisuke Ono, Fabienne C. Fiesel, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin‐Taner, J. Raphael Gibbs, Bryan J. Traynor, Clifton L. Dalgard, Rodolfo Savica, Jonathan Graff‐Radford, Ronald C. Petersen, R. Ross Reichard, Neill R. Graff‐Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Wolfdieter Springer, Ziv Gan‐Or, Emmanuel Mignot, Sonja W. Scholz, Dennis W. Dickson, Owen A. Ross   +34 more
wiley   +1 more source