Results 111 to 120 of about 805,763 (399)

An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, EarlyView.
ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

Scientific Reports, 2019
Primary aldosteronism (PA) is the most frequent form of secondary arterial hypertension. Mutations in different genes increase aldosterone production in PA, but additional mechanisms may contribute to increased cell proliferation and aldosterone ...
Rami M. El Zein, Audrey H. Soria, Jose Felipe Golib Dzib, Amanda J. Rickard, Fabio L. Fernandes-Rosa, Benoit Samson-Couterie, Isabelle Giscos-Douriez, Angélique Rocha, Marko Poglitsch, Celso E. Gomez-Sanchez, Laurence Amar, Norbert B. Ghyselinck, Arndt Benecke, Maria-Christina Zennaro, Sheerazed Boulkroun   +14 more
doaj   +1 more source

Morphological and Histological Studies on the Adrenal Gland of the Chicken (Gallus domesticus)

The Journal of Poultry Science, 2012
Morphological and histological studies of the adrenal gland of the adult White Leghorn chicken (Gallus domesticus) were performed. Macro- and microscopic observations of azan- or formal-dichromate stained (to observe the chromaffin reaction of adrenal ...
Kober A.K.M. Humayun, Masato Aoyama, Shoei Sugita   +2 more
doaj   +1 more source

Morphological and functional manifestations of rat adrenal-cortex response to sodium bromide administration under hypodynamic stress [PDF]

Functional and morphological manifestations of adrenal cortex response to hypodynamia (2-hr immobilization on an operating table) under the influence of bromine preparations were studied. The sodium bromide was administered intraperitoneally in 100, 250,
Kirichek, L. T., Zholudeva, V. I.
core   +1 more source

Genetic background influences tumour development in heterozygous Men1 knockout mice [PDF]

, 2020
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreatic and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroidism (FIHP)
Christie, Paul T., Javid, Mahsa, Kooblall, Kreepa G., Lines, Kate E., Mallon, Ann-Marie, Newey, Paul J., Piret, Sian E., Reed, Anita Ac, Simon, Michelle, Stevenson, Mark, Thakker, Rajesh V., Walls, Gerard V.   +11 more
core   +2 more sources

Evaluation of the Pharmacokinetics, Disposition, and Metabolism of Miricorilant, a Novel Glucocorticoid Receptor Modulator for the Treatment of Metabolic Dysfunction‐Associated Steatohepatitis in Nonclinical and Clinical Studies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Miricorilant is a novel selective glucocorticoid receptor (GR) modulator with mixed agonist/antagonist effects at the GR and modest antagonism at the mineralocorticoid receptor that is being developed for the treatment of metabolic dysfunction‐associated steatohepatitis.
Hazel J. Hunt, Kirsteen M. Donaldson, Jeevan R. Kunta, Joseph M. Custodio   +3 more
wiley   +1 more source

Adrenal Cortex

Definitions, 2020
F. Wondisford
semanticscholar   +2 more sources

FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development [PDF]

, 2013
Developmental signalling pathways are implicated in the formation and maintenance of the adrenal gland, but their roles are currently not well defined. In recent years it has emerged that Sonic hedgehog (Shh) and Wnt/β catenin signalling are crucial for ...
Berg, Beuschlein, Chida, Ching, Chu, Chuang, Crickard, De Moerlooze, Fogarty, Grose, Guasti, Hajihosseini, Halder, Hatano, Huang, Karpac, Kim, Kim, Kim, King, Laufer, Laufer, Lavine, Leonardo Guasti, Lepique, Luo, Mao, Mavila, Peter J. King, Ramirez, Reddy, Revest, Richard Grose, Sekhon, Smas, Sul, Tristan McKay, Turner, Veltmaat, W.C. Candy Sze, Zhang, Zhang   +41 more
core   +2 more sources

A Study of the Adrenal Cortex in the Mouse and Its Relation to the Gonads

, 1928
In 1920 Masui and Tamura published a study of the adrenals of mice (20), and drew attention to the larger size of the female adrenal as compared with that of the male.
R. Deanesly
semanticscholar   +1 more source

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

Medicine Bulletin, EarlyView.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao, Ruolan Li, Jingdong Zhao, Ruiqi Sun, Shuo Zhang, Qiong Pan, Hongyan Lu, Jin Chai   +7 more
wiley   +1 more source