Results 171 to 180 of about 79,543 (252)
ABSTRACT Prenatal stress has broad detrimental consequences for neurodevelopment, with potential sensitive periods within gestation affecting specific developmental systems. We examined the effects of prenatal stress timing, level, and fluctuations on three markers of sympathetic nervous system activity: infant salivary alpha amylase (sAA), fear, and ...
Cecilia Martinez‐Torteya +7 more
wiley +1 more source
‐Pi infusion significantly improved locomotor activity and exploratory behavior in aging mice; its bioactive compounds may have direct effects on behavior, which may be accompanied by a putative indirect effect involving the gut microbiota. ‐Pi infusion consumption restored commensal Bacilli levels and caused a significant decrease in Clostridia levels
Yulia Kroupitski +7 more
wiley +1 more source
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley +1 more source
ABSTRACT Background Our study aimed to investigate the association between social isolation and chest pain, and to evaluate the relationship between social isolation and all‐cause mortality stratified by the presence or absence of chest pain among participants.
Xiaozhe Zheng +7 more
wiley +1 more source
Visual impairment has been associated with an increased risk of depression in patients with diabetes, yet no studies have explored the role of visual function as a predictor of depression. To develop and validate a predictive model for depression risk in patients with Type 2 Diabetes Mellitus (T2DM) in community health settings, incorporating a visual ...
Rong‐song Sun +8 more
wiley +1 more source
ABSTRACT Introduction Distinguishing adrenocortical carcinoma (ACC) from adenoma is often difficult, particularly in hormonally active tumors with borderline histologic features. Case Presentation A 55‐year‐old woman presented with abdominal distension and central obesity. Hormonal evaluation confirmed ACTH‐independent Cushing's syndrome.
Fumihiro Ito +4 more
wiley +1 more source
An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract
ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston +2 more
wiley +1 more source
From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi +7 more
wiley +1 more source

