Results 31 to 40 of about 805,763 (399)

Congenital adrenal hyperplasia - current insights in pathophysiology, diagnostics and management.

Endocrine reviews, 2021
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to chronic overstimulation of the adrenal cortex and accumulation of ...
H. Claahsen-van der Grinten, P. Speiser, S. Ahmed, W. Arlt, R. Auchus, H. Falhammar, C. Flück, L. Guasti, A. Huebner, B. Kortmann, N. Krone, D. Merke, W. Miller, A. Nordenström, Nicole Reisch, D. Sandberg, N. Stikkelbroeck, P. Touraine, Agustini Utari, S. Wudy, P. White   +20 more
semanticscholar   +1 more source

Development of Adrenocorticotrophic Hormone Cells of Adenohypophysis–Adrenal Cortex Axis of Long-tailed Monkey (Macaca fascicularis) during Pre and Postnatal Period

Jurnal Kedokteran Hewan, 2008
The objective of this study is to observe the relationship of development of adrenocorticotropic hormone (ACTH) cells of adenohypophysis–adrenal cortex axis during pre and postnatal period of longtailed monkey (Macaca fascicularis). Five fetuses aged 70,
Nurhidayat Nurhidayat, Ika K. Syarifah, Supratikno Supratikno, Sri Wahyuni   +3 more
doaj   +1 more source

MORPHOLOGICAL STUDY OF ADRENAL GLAND IN PRENATAL AND POSTNATAL PERIODS OF DOMESTIC RABBIT (ORYCTOLAGUSCUNICULUS) [PDF]

Basrah Journal of Veterinary Research, 2013
The developmental study of adrenal gland has been done on the local rabbit fetuses and neonate, which including a morphological and histological description of the adrenal gland.
Farhan Owda Rabie
doaj   +1 more source

Late diagnosis of primary chronic adrenal insufficiency in the framework of autoimmune polyglandular syndrome type 2. Clinical observation

Лечащий Врач, 2023
Chronic adrenal insufficiency is caused by insufficient secretion of hormones by the adrenal cortex due to dysfunction of one or more links of the hypothalamic-pituitary-adrenal system.
V. G. Chobitko, A. P. Belova
doaj   +1 more source

PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.

JCI Insight, 2018
The adrenal cortex undergoes remodeling during fetal and postnatal life. How zona reticularis emerges in the postnatal gland to support adrenarche, a process whereby higher primates increase prepubertal androgen secretion, is unknown.
T. Dumontet, I. SAHUT-BARNOLA, A. Septier, N. Montanier, I. Plotton, F. Roucher-Boulez, V. Ducros, A. LEFRANCOIS-MARTINEZ, Jean-Christophe Pointud, M. Zubair, K. Morohashi, D. Breault, P. Val, Antoine Martinez   +13 more
semanticscholar   +1 more source

Contribution of the adrenal gland to the production of androstenedione and testosterone during the first two years of life [PDF]

, 1986
Androstenedione and testosterone were measured in whole adrenal glands of 56 previously healthy boys who died suddenly between birth and 2 yr of age. In each adrenal gland, the concentration of androstenedione considerably exceeded that of testosterone ...
Bidlingmaier, F., Dörr, H. G., Eisenmenger, Wolfgang, Knorr, D., Kuhnle, U.   +4 more
core   +1 more source

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance The adrenal cortex plays a central role in regulating body homeostasis through production of glucocorticoids and mineralocorticoids that control metabolism, inflammation, and blood pressure.
M. Mathieu, C. Drelon, S. Rodriguez, H. Tabbal, A. Septier, C. Damon-Soubeyrand, T. Dumontet, A. Berthon, I. SAHUT-BARNOLA, C. Djari, M. Batisse-Lignier, Jean-Christophe Pointud, Damien Richard, G. Kerdivel, Marie-Ange Calméjane, V. Boeva, I. Tauveron, A. LEFRANCOIS-MARTINEZ, Antoine Martinez, P. Val   +19 more
semanticscholar   +1 more source

The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex [PDF]

Archives of Biological Sciences, 2013
Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The proliferative and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient ...
Petrović-Kosanović Dragana, Ajdžanović V., Čakić-Milošević Maja, Koko Vesna, Milošević Verica   +4 more
doaj   +1 more source

New directions for the treatment of adrenal insufficiency [PDF]

, 2015
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen, Allende, Badylak, Bancos, Berkes, Birke, Buaas, Chamoux, Chamoux, Clipsham, Cogger, Cox, Crawford, Drucker, Dubernard, El-Khairi, Else, Faulk, Fayard, Franksson, Freedman, Gallo-Payet, Gondo, Gondo, Grodstein, Guasti, Guasti, Hardy, Hardy, Hardy, Hardy, Hatano, Huang, Huang, Ibbertson, Jadhav, Kearns, Kim, King, Laufer, Ludwig, Luo, Mazilu, Parker, Sancho-Martinez, Schimmer, Schnabel, Sonoyama, Takahashi, Tanaka, Teebken, Thomas, Thomas, Thomas, Thomas, Thomas, Val, Val, Vierbuchen, Vouillarmet, Walczak, Walczak, Wei, Wilhelm, Wong, Yazawa, Yazawa, Yazawa, Yazawa, Zupekan   +69 more
core   +2 more sources

Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies

International Journal of Pediatrics, 2018
Adrenal insufficiency may result from a wide variety of congenital or acquired disorders of hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is the cause of primary adrenal insufficiency, while secondary ...
Sasigarn A. Bowden, Rohan Henry
doaj   +1 more source