Results 31 to 40 of about 783,304 (397)
PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.
JCI Insight, 2018 The adrenal cortex undergoes remodeling during fetal and postnatal life. How zona reticularis emerges in the postnatal gland to support adrenarche, a process whereby higher primates increase prepubertal androgen secretion, is unknown.
T. Dumontet +13 more
semanticscholar +1 more source
Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland [PDF]
, 2019 The evidence from post-mortem biochemical studies conducted on cortisol and catecholamines suggest that analysis of the adrenal gland could provide useful information about its role in human pathophysiology and the stress response.
Alibrandi A. +10 more
core +1 more source
FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development [PDF]
, 2013 Developmental signalling pathways are implicated in the formation and maintenance of the adrenal gland, but their roles are currently not well defined. In recent years it has emerged that Sonic hedgehog (Shh) and Wnt/β catenin signalling are crucial for ...
Berg +41 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance The adrenal cortex plays a central role in regulating body homeostasis through production of glucocorticoids and mineralocorticoids that control metabolism, inflammation, and blood pressure.
M. Mathieu +19 more
semanticscholar +1 more source
The effects of acute heat stress on proliferative and apoptotic processes in the rat adrenal cortex [PDF]
Archives of Biological Sciences, 2013 Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The proliferative and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient ...
Petrović-Kosanović Dragana +4 more
doaj +1 more source
Roles of Bone Morphogenetic Protein-6 in Aldosterone Regulation by Adrenocortical Cells [PDF]
, 2010 Aldosterone production occurs in the adrenal cortex, and is regulated primarily by angiotensin II (Ang II), potassium and adrenocorticotropin (ACTH). In the presence of the aldosterone stimulators, steroidogenesis is further governed by local autocrine ...
Inagaki, Kenichi +4 more
core +1 more source
Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies
International Journal of Pediatrics, 2018 Adrenal insufficiency may result from a wide variety of congenital or acquired disorders of hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is the cause of primary adrenal insufficiency, while secondary ...
Sasigarn A. Bowden, Rohan Henry
doaj +1 more source
PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development
Nature Communications, 2016 Adrenal cortex physiology relies on functional zonation, essential for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona fasciculata (ZF).
C. Drelon +18 more
semanticscholar +1 more source
The mind–body problem: Circuits that link the cerebral cortex to the adrenal medulla
Proceedings of the National Academy of Sciences of the United States of America, 2019 Which regions of the cerebral cortex are the origin of descending commands that influence internal organs? We used transneuronal transport of rabies virus in monkeys and rats to identify regions of cerebral cortex that have multisynaptic connections with
R. Dum, D. Levinthal, P. Strick
semanticscholar +1 more source
Genetics of tumors of the adrenal cortex.
Endocrine-Related Cancer, 2017 This review describes the molecular alterations observed in the various types of tumors of the adrenal cortex, excluding Conn adenomas, especially the alterations identified by genomic approaches these last five years.
Fidéline Bonnet-Serrano, J. Bertherat
semanticscholar +1 more source