Results 41 to 50 of about 805,763 (399)
PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development
Nature Communications, 2016 Adrenal cortex physiology relies on functional zonation, essential for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona fasciculata (ZF).
C. Drelon +18 more
semanticscholar +1 more source
Label-free enrichment of adrenal cortical progenitor cells using inertial microfluidics. [PDF]
, 2012 Passive and label-free isolation of viable target cells based on intrinsic biophysical cellular properties would allow for cost savings in applications where molecular biomarkers are known as well as potentially enable the separation of cells with little-
Brinckerhoff, Tatiana Z +4 more
core +2 more sources
The mind–body problem: Circuits that link the cerebral cortex to the adrenal medulla
Proceedings of the National Academy of Sciences of the United States of America, 2019 Which regions of the cerebral cortex are the origin of descending commands that influence internal organs? We used transneuronal transport of rabies virus in monkeys and rats to identify regions of cerebral cortex that have multisynaptic connections with
R. Dum, D. Levinthal, P. Strick
semanticscholar +1 more source
Genetics of tumors of the adrenal cortex.
Endocrine-Related Cancer, 2017 This review describes the molecular alterations observed in the various types of tumors of the adrenal cortex, excluding Conn adenomas, especially the alterations identified by genomic approaches these last five years.
F. Bonnet-Serrano, J. Bertherat
semanticscholar +1 more source
The Hormone of the Adrenal Cortex
Science, 1930 We have previously1 demonstrated that an extract which will definitely prolong the lives and ameliorate the symptoms of adrenal-ectomized cats can be made from the adrenal cortex.We have proposed t...
F A, Hartman, K A, Brownell
openaire +2 more sources
Functional Zonation of the Adult Mammalian Adrenal Cortex
Frontiers in Neuroscience, 2016 The standard model of adrenocortical zonation holds that the three main zones, glomerulosa, fasciculata, and reticularis each have a distinct function, producing mineralocorticoids (in fact just aldosterone), glucocorticoids, and androgens respectively ...
G. Vinson
semanticscholar +1 more source
Endokrynologia Polska, 2020 INTRODUCTION: Pheochromocytomas in hereditary syndromes tend to grow multifocal with adrenal involvement on both sides. Surgical treatment with bilateral adrenalectomy inevitably leads to life-long hormonal dependence, which significantly affects quality
Kornelia Hasse-Lazar +13 more
doaj +1 more source
Signaling Interactions in the Adrenal Cortex
Frontiers in Endocrinology, 2016 The major physiological stimuli of aldosterone secretion are angiotensin II (AII) and extracellular K+, whereas cortisol production is primarily regulated by corticotropin (ACTH) in fasciculata cells.
A. Spät, L. Hunyady, G. Szanda
semanticscholar +1 more source
Single-cell and spatial transcriptomics analysis of human adrenal aging
Molecular MetabolismObjective: The human adrenal cortex comprises three functionally and structurally distinct layers that produce layer-specific steroid hormones. With aging, the human adrenal cortex undergoes functional and structural alteration or “adrenal aging ...
Norifusa Iwahashi +18 more
doaj +1 more source
Development and function of the fetal adrenal
Reviews in Endocrine & Metabolic Disorders, 2022 The adrenal cortex undergoes multiple structural and functional rearrangements to satisfy the systemic needs for steroids during fetal life, postnatal development, and adulthood.
Emanuele Pignatti +2 more
semanticscholar +1 more source