Editorial: Adrenal Cortex: From Physiology to Disease [PDF]
The Editorial on the Research Topic Adrenal cortex: from physiology to disease The adrenal gland plays essential roles in the control of body homeostasis, stress, and immune responses. The adrenal cortex represents up to 90% of the gland and is specialized in the production of adrenal steroids.
Val, Pierre, Martinez, Antoine
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CONGENITAL ADRENAL CORTEX HYPERPLASIA IN A NEWBORN (CLINICAL CASE)
Congenital adrenal cortex hyperplasia combines a group of monogenic diseases with an autosomal recessive fashion based on defects in enzymes or transport proteins involved in adrenal steroidogenesis.
N.M. Kretsu +3 more
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Medical Treatment of Alcoholic Liver Disease
Alcoholic liver disease is a major cause of liver disease that results in significant morbidity and mortality in Korea. Abstinence is the most important strategy to prevent disease progression.
Do Seon Song
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Development of adrenal 3-dimensional spheroid cultures: potential for the treatment of adrenal insufficiency and neurodegenerative diseases [PDF]
Aim: Regenerative and curative strategies would be desirable for neurodegenerative and adrenal diseases, and multipotent adrenal stem cells are considered as promising biological tools for this purpose.
Charlotte Steenblock +6 more
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Seizure and coma secondary to Conn’s syndrome: a case report
Background Conn’s syndrome is a curable condition if identified properly. It is characterized by autonomous secretion of aldosterone from the adrenal gland cortex. Its morbidity is related to the increased risk of cardiovascular diseases.
Eiman Alseddeeqi +2 more
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Adrenal crisis and mortality rate in adrenal insufficiency and congenital adrenal hyperplasia
Primary adrenal insufficiency (PAI) is characterized by the inability of the adrenal cortex to produce sufficient amounts of glucocorticoids and/or mineralocorticoids.
Lia Mesquita Lousada +2 more
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Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α [PDF]
The incidence and prevalence of inflammatory bowel diseases (IBDs) are rapidly increasing worldwide. IBDs are considered an emerging problem not only in Western countries but also in developing counties.
Jihye Park, Jae Hee Cheon
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Genome editing in the adrenal gland: a novel strategy for treating congenital adrenal hyperplasia [PDF]
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency leads to high morbidity and mortality, despite the availability of life-saving corticosteroid replacement therapy.
Eva B. van Dijk +3 more
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Eplerenone–A novel Mineralocorticoid receptor antagonist for the clinical application
Aldosterone is produced from the zona glomerulosa of the adrenal cortex in the adrenal gland, which is main mineralocorticoid hormone. Upon binding the mineralocorticoid receptor, it regulates sodium and potassium absorption, secretion, and retention ...
Nan-Nan Wu, Yuan-Yuan Zhang, Dong Zhao
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Adrenal Cytomegaly: Two Cases Detected by Prenatal Diagnosis
We report our experience with two cases of adrenal cytomegaly, both of which were detected as cystic adrenal masses during prenatal ultrasonographic examinations. In Case 1, a left suprarenal cystic mass was detected in the fetus at 25 weeks of gestation.
Shin-ichi Noguchi +3 more
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