The human adrenal cortex: growth control and disorders
Clinics, 2018 This review summarizes key knowledge regarding the development, growth, and growth disorders of the adrenal cortex from a molecular perspective. The adrenal gland consists of two distinct regions: the cortex and the medulla.
Jean Lucas Kremer +2 more
exaly +4 more sources
The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease [PDF]
International Journal of Molecular Sciences, 2021 Many adrenocortical diseases are more prevalent in women than in men, but the reasons underlying this sex bias are still unknown. Recent studies involving gonadectomy and sex hormone replacement experiments in mice have shed some light onto the molecular
Andreas Schedl, Rodanthi Lyraki
exaly +3 more sources
Transgenic Mouse Models to Study the Development and Maintenance of the Adrenal Cortex [PDF]
International Journal of Molecular Sciences, 2022 The cortex of the adrenal gland is organized into concentric zones that produce distinct steroid hormones essential for body homeostasis in mammals. Mechanisms leading to the development, zonation and maintenance of the adrenal cortex are complex and ...
Alexandre Boyer +2 more
exaly +3 more sources
Proteomic profiling of the extracellular matrix in the human adrenal cortex [PDF]
Matrix Biology PlusThe extracellular matrix (ECM) comprises macromolecules that shape a complex three-dimensional network. Filling the intercellular space and playing a crucial role in the structure and function of tissues, ECM regulates essential cellular processes such ...
Jean Lucas Kremer +6 more
doaj +2 more sources
Disorders of the adrenal cortex: Genetic and molecular aspects [PDF]
Frontiers in Endocrinology, 2022 Adrenal cortex produces glucocorticoids, mineralocorticoids and adrenal androgens which are essential for life, supporting balance, immune response and sexual maturation.
Georgia Pitsava +4 more
doaj +2 more sources
Ectopic adrenal cortex associated with epididymal malformation in adult: A clinical case report [PDF]
Urology Case Reports, 2021 To report a case of unusual ectopic adrenal cortex in adult.A 35-year-old male consulted for vasectomy. During the procedure, a small right epididymal cyst was incidentally found. The ductus deferens was not identified.
Ph Deslarzes +3 more
doaj +2 more sources
An integrated single-cell analysis of human adrenal cortex development [PDF]
JCI Insight, 2023 The adrenal glands synthesize and release essential steroid hormones such as cortisol and aldosterone, but many aspects of human adrenal gland development are not well understood.
Ignacio del Valle +16 more
doaj +2 more sources
Embryonic Development and Adult Regeneration of the Adrenal Gland [PDF]
Endocrinology and Metabolism, 2020 The adrenal gland plays a pivotal role in an organism’s health span by controlling the endocrine system. Decades of research on the adrenal gland have provided multiscale insights into the development and maintenance of this essential organ.
Ji-Hoon Kim, Man Ho Choi
doaj +1 more source
The Possible Ameliorating Effect of Barley Grain on the Histological Structure of the Adrenal Cortex in Streptozotocin (STZ)-induced Diabetes in Adult Male Albino Rats [PDF]
The Egyptian Journal of Histology, 2020 Background: Diabetes is one of the most common endocrine disorders caused by lack of, or reduced insulin action leading to increase in blood glucose level and metabolic disorders in the body.
Mona Soliman, Dalia Noya
doaj +1 more source
Comparison of miRNA expression profiles in pituitary–adrenal axis between Beagle and Chinese Field dogs after chronic stress exposure [PDF]
PeerJ, 2016 MicoRNAs (miRNAs), usually as gene regulators, participate in various biological processes, including stress responses. The hypothalamus–pituitary–adrenal axis (HPA axis) is an important pathway in regulating stress response.
Wei Luo +5 more
doaj +2 more sources