Results 1 to 10 of about 52,313 (257)
Development and organisation of gonadal steroidogenesis in bony fishes - A review
Aquaculture and Fisheries, 2021 Gonadal steroidogenesis is pivotal to synchronize various reproductive stages including sexual development, growth and maturation. In all vertebrates including teleost, steroidogenesis is triggered by the mobilization of cholesterol by steroidogenic ...
Senthilkumaran B
exaly +4 more sources
Cells, 2023 DEHP is an endocrine disruptor that interferes with the function of the female reproductive system. Several studies suggested that DEHP affects steroidogenesis in human and rodent granulosa cells (GC).
Biljana Tesic +7 more
doaj +2 more sources
Hormones and Signaling Pathways Involved in the Stimulation of Leydig Cell Steroidogenesis
Endocrines, 2023 Leydig cells, located in the testis interstitial space, are the primary source of testosterone in males. Testosterone plays critical roles in both reproductive and metabolic functions and therefore is essential for male health.
Karine de Mattos +2 more
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The Expanding Role of Mitochondria, Autophagy and Lipophagy in Steroidogenesis
Cells, 2021 The fundamental framework of steroidogenesis is similar across steroidogenic cells, especially in initial mitochondrial steps. For instance, the START domain containing protein-mediated cholesterol transport to the mitochondria, and its conversion to ...
Geetika Bassi +2 more
doaj +2 more sources
AMPK/ULK1 enhances mitophagy and steroidogenesis in duck Granulosa cells under heat exposure [PDF]
Poultry ScienceMitochondria play crucial roles in energy metabolism and steroidogenesis. Heat stress suppresses steroidogenesis in ovarian granulosa cells (GCs) and impairs poultry reproduction.
Xiaozhi Zhan +8 more
doaj +2 more sources
Ecotoxicology and Environmental Safety, 2021 Triclosan (TCS) is an endocrine-disrupting chemical (EDC), which is used ubiquitously as an antimicrobial ingredient in healthcare products and causes contamination in the environment such as air, water, and biosolid-amended soil.
Yatao Du +8 more
doaj +2 more sources
BMI1 Drives Steroidogenesis Through Epigenetically Repressing the p38 MAPK Pathway
Frontiers in Cell and Developmental Biology, 2021 Testosterone biosynthesis progressively decreases in aging males primarily as a result of functional changes to Leydig cells. Despite this, the mechanisms underlying steroidogenesis remain largely unclear.
Jun Yu +13 more
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The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
Reproductive Biology and Endocrinology, 2018 Background Cytokines and hormones, including insulin, are known to modulate the hypothalamic-pituitary-testes axis and steroidogenesis, both centrally and peripherally.
Kristian Leisegang, Ralf Henkel
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The role of proteins implicated in skin steroidogenesis in acne vulgaris development [PDF]
Vestnik Dermatologii i Venerologii, 2023 Background. Acne vulgaris belongs to androgen-dependent diseases where androgens cause sebaceous gland hypertrophy with a subsequent enlargement of sebum production. Aims.
Andrey K. Kirichenko +5 more
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Frontiers in Endocrinology, 2022 Infection and inflammation are relevant entities of male reproductive disorders that can lead to sub-/infertility. Associated damage of the testis of affected men and in rodent models include leukocytic infiltration, edema formation, fibrosis, germ cell ...
Hiba Hasan +3 more
semanticscholar +1 more source