Results 41 to 50 of about 38,975 (250)
Animal Research and One Health, EarlyView.This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen +2 more
wiley +1 more source
Preclinical and Clinical Research Models of Prostate Cancer: A Brief Overview
Life, 2022 The incidence and mortality from prostate cancer (PCa) are on the rise which poses a major public health concern worldwide. In this narrative review, we have summarized the characteristics of major in vitro and in vivo PCa models including their utility ...
Debasish Basak +3 more
doaj +1 more source
, 2018 Data associated with publication on High-Throughput H295R Steroidogenesis Assay Approach to Characterize Effects on Steroidogenesis.
EPA's National Center for Computational Toxicology (5039467)
core +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
SIRT1: A Key Player in Male Reproduction
Life, 2022 Reproduction is the way to immortality for an individual, and it is essential to the continuation of the species. Sirtuins are involved in cellular homeostasis, energy metabolism, apoptosis, age-related problems, and sexual reproduction. Sirtuin 1 (SIRT1)
Muhammad Babar Khawar +2 more
doaj +1 more source
Food Safety and Health, EarlyView.Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad +3 more
wiley +1 more source
Studies on Steroidogenesis in the Oocyte
Folia Endocrinologica Japonica, 1982 The steroid hormone has an important role in the early stages of reproduction. There has been abundant histochemical evidence that oocytes contain steroid hormones and are able to synthesize these hormones. But there have been few methods of analyzing one oocyte biochemically because it is too small and light.
TSUTSUMI, Osamu +2 more
openaire +3 more sources
Metabolomic fingerprints of clustered preterm and term neonates – a pilot study
Frontiers in EndocrinologyIntroductionAdrenal steroidogenesis plays a pivotal role in neonatal adaptation, and advanced steroid profiling offers novel insights into disease risks and personalized management strategies.
Miłosz Lorek +6 more
doaj +1 more source
Animals, 2022 Selenium (Se)-deficient soils necessitate supplementation of this mineral to the diet of forage-grazing cattle. Functionally, Se is incorporated into selenoproteins, some of which function as important antioxidants.
Sarah N. Carr +5 more
doaj +1 more source
Insight into the role of TXNRD2 in steroidogenesis through a novel homozygous TXNRD2 splice variant. [PDF]
OBJECTIVE Adrenal cortisol production occurs through a biosynthetic pathway which depend on NADH and NADPH for energy supply. The mitochondrial respiratory chain and the reactive oxygen species (ROS) detoxification system are therefore important for ...
Sauter, Kay-Sara +11 more
core +1 more source