Results 21 to 30 of about 43,028 (255)
Journal of Pharmacological Sciences, 2003 : To examine effects of volatile anesthetics (VAs) on steroidogenesis, cell suspensions of isolated bovine adrenocortical cells were incubated with several steroidogenic agents in the presence or absence of halothane and sevoflurane.
Eiji Masaki +4 more
doaj +1 more source
Bisphenol A and ovarian steroidogenesis [PDF]
Fertility and Sterility, 2016 Bisphenol A is widely used as a component in polycarbonate plastics for food and beverage packaging, epoxy linings for canned foods, and dental sealants, among other applications. Experimental literature demonstrates BPA's affinity for estrogen receptors and downstream effects on estrogen-responsive genes.
Michael S, Bloom +2 more
openaire +2 more sources
The Journal of Clinical Investigation, 2022 Through their ability to regulate gene expression in most organs, glucocorticoid (GC) hormones influence numerous physiological processes and are therefore key regulators of organismal homeostasis.
Vijay K. Yadav +4 more
doaj +1 more source
The anti-epileptic drug Valproic Acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro [PDF]
, 2012 Valproic acid (VPA) is used widely to treat epilepsy and bipolar disorder. Women undergoing VPA treatment reportedly have an increased incidence of polycystic ovarian syndrome (PCOS)-like symptoms including hyperandrogenism and oligo- or amenorrhoea.
Knight, PG +19 more
core +2 more sources
Discovery of autophagy as a universal mechanism for sex steroid synthesis in human ovary and testis
Autophagy Reports, 2023 We recently discovered that lipophagy is a key mechanism to provide free cholesterol required for steroid biosynthesis in human ovary and testis. Pharmacological or genetic inhibition of autophagy by silencing of the autophagy-related (ATG) genes BECN1 ...
Yashar Esmaeilian +6 more
doaj +1 more source
Molecular Mechanisms of Steroid Hormone Biosynthesis and Action
, 2023 Steroids are essential hormones that regulate biological processes across their lifespan. Steroid hormone production and action must be tightly controlled otherwise there can be detrimental effects on physiological function leading to disease.
core +1 more source
Toxins, 2023 Deoxynivalenol (DON) is a major mycotoxin present in animal feed and negatively affects growth and reproduction in farm species, including pigs and cattle.
Angelica D. Reyes-Perea +4 more
doaj +1 more source
Insulin increases De Novo Steroidogenesis in prostate cancer cells [PDF]
, 2011 Androgen-dependent pathways regulate maintenance and growth of normal and malignant prostate tissues. Androgen deprivation therapy (ADT) exploits this dependence and is used to treat metastatic prostate cancer; however, regression initially seen with ADT
Herington, Adrian +19 more
core +1 more source
Korean Ginseng Berry Extract Enhances the Male Steroidogenesis Enzymes In Vitro and In Vivo
The World Journal of Men's Health, 2023 Purpose: Testosterone hormonal replacement is the most commonly prescribed solution for men with reproductive issues; however, this treatment has various drawbacks.
Hyun Joo Chung +6 more
doaj +1 more source
The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
Reproductive Biology and Endocrinology, 2018 Background Cytokines and hormones, including insulin, are known to modulate the hypothalamic-pituitary-testes axis and steroidogenesis, both centrally and peripherally.
Kristian Leisegang, Ralf Henkel
doaj +1 more source