Results 11 to 20 of about 52,313 (257)

Expression of genes and enzymes involved in ovarian steroidogenesis in relation to human follicular development

open access: yesFrontiers in Endocrinology, 2023
Introduction Granulosa cells (GCs) and theca cells (TCs) play a pivotal role in human ovarian steroidogenesis, facilitating the conversion of cholesterol into sex steroids that regulate normal reproductive function.
M. Zheng   +5 more
semanticscholar   +1 more source

Different types of bisphenols alter ovarian steroidogenesis: Special attention to BPA

open access: yesHeliyon, 2023
Endocrine disruptors such as bisphenol A (BPA) and some of its analogues, including BPS, BPAF, and BPE, are used extensively in the manufacture of plastics.
H. Shoorei   +5 more
semanticscholar   +1 more source

Fatty acids suppress the steroidogenesis of the MA-10 mouse Leydig cell line by downregulating CYP11A1 and inhibiting late-stage autophagy

open access: yesScientific Reports, 2021
Obese men have lower circulating testosterone than men with an optimal body mass index. Elevated fatty acids (FAs) caused by obesity have been reported to suppress the steroidogenesis of Leydig cells.
Chien Huang   +7 more
doaj   +1 more source

Defects of steroidogenesis [PDF]

open access: yesJournal of Endocrinological Investigation, 2010
In the biosynthesis of steroid hormones the neutral lipid cholesterol, a normal constituent of lipid bilayers is transformed via a series of hydroxylation, oxidation, and reduction steps into a vast array of biologically active compounds: mineralocorticoids, glucocorticoids, and sex hormones.
BIASON LAUBER A   +3 more
openaire   +4 more sources

Prohibitin-1 plays a regulatory role in Leydig cell steroidogenesis

open access: yesiScience, 2022
Summary: Mitochondria are essential for steroidogenesis. In steroidogenic cells, the initiation of steroidogenesis from cholesterol occurs on the matrix side of the inner mitochondrial membrane by the enzyme P450scc. This requires cholesterol import from
Geetika Bassi, Suresh Mishra
doaj   +1 more source

Revisiting steroidogenesis and its role in immune regulation with the advanced tools and technologies

open access: yesGenes and Immunity, 2021
Historically tools and technologies facilitated scientific discoveries. Steroid hormone research is not an exception. Unfortunately, the dramatic advancement of the field faded this research area and flagged it as a solved topic.
Souraditya Chakraborty   +2 more
semanticscholar   +1 more source

Arsenic exposure diminishes ovarian follicular reserve and induces abnormal steroidogenesis by DNA methylation.

open access: yesEcotoxicology and Environmental Safety, 2022
Arsenic contamination is a worldwide public health problem, and the effect of arsenic on male reproduction has been extensively studied; however, data on the biotoxicity of arsenic in terms of female reproduction are more scarce.
Yiqin Chen   +9 more
semanticscholar   +1 more source

Fluorene-9-bisphenol regulates steroidogenic hormone synthesis in H295R cells through the AC/cAMP/PKA signaling pathway

open access: yesEcotoxicology and Environmental Safety, 2022
Fluorene-9-bisphenol (BHPF), which has been used as a substitute for bisphenol A (BPA) in consumer goods and industrial products, can be detected in environmental media and human urine. BHPF has been reported to have endocrine-disrupting effects, whereas
Yuan Huang   +7 more
doaj   +1 more source

Intestinal steroidogenesis [PDF]

open access: yesSteroids, 2015
Steroids are fundamental hormones that control a wide variety of physiological processes such as metabolism, immune functions, and sexual characteristics. Historically, steroid synthesis was considered a function restricted to the adrenals and the gonads.
Bouguen, Guillaume   +4 more
openaire   +4 more sources

Immune Cells as Critical Regulators of Steroidogenesis in the Testis and Beyond

open access: yesFrontiers in Endocrinology, 2022
Steroidogenesis is an essential biological process for embryonic development, reproduction, and adult health. While specific glandular cells, such as Leydig cells in the testis, are traditionally known to be the principal players in steroid hormone ...
Xiaowei Gu   +3 more
semanticscholar   +1 more source

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