Results 11 to 20 of about 38,975 (250)
Perturbing local steroidogenesis to improve breast cancer immunity [PDF]
Nature CommunicationsBreast cancer, particularly triple-negative breast cancer (TNBC), evades the body’s immune defences, in part by cultivating an immunosuppressive tumour microenvironment.
Qiuchen Zhao +12 more
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Translocator protein and steroidogenesis [PDF]
Biochemical Journal, 2018 Two interesting papers by Barren et al. and Owen et al. have been very recently published in Biochemical Journal, reporting the role of translocator protein (TSPO) in steroidogenesis. The involvement of TSPO in the steroid biosynthesis has been suggested
Eleonora Da Pozzo +5 more
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Journal of Pharmacological Sciences, 2003 : To examine effects of volatile anesthetics (VAs) on steroidogenesis, cell suspensions of isolated bovine adrenocortical cells were incubated with several steroidogenic agents in the presence or absence of halothane and sevoflurane.
Eiji Masaki +4 more
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Chemical suppression of steroidogenesis.
Environmental Health Perspectives, 1981 A large number of chemicals are known to interfere with steroidogenesis in the adrenal cortex and other tissues. Many xenobiotics inhibit steroid hormone production as a result of interactions with cytochrome P-450-containing hydroxylases in adrenal ...
Colby, H D
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Defects of steroidogenesis [PDF]
Journal of Endocrinological Investigation, 2010 In the biosynthesis of steroid hormones the neutral lipid cholesterol, a normal constituent of lipid bilayers is transformed via a series of hydroxylation, oxidation, and reduction steps into a vast array of biologically active compounds: mineralocorticoids, glucocorticoids, and sex hormones.
BIASON LAUBER A +3 more
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Intestinal steroidogenesis [PDF]
Steroids, 2015 Steroids are fundamental hormones that control a wide variety of physiological processes such as metabolism, immune functions, and sexual characteristics. Historically, steroid synthesis was considered a function restricted to the adrenals and the gonads.
Bouguen, Guillaume +4 more
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"Ex vivo" and "in vivo" studies to assess chemical effects on steroidogenesis in fish: development and application of methods [PDF]
, 2011 The aquatic environment receives many chemical substances of natural or anthropogenic origin, which can influence the endocrine functions and health of wildlife.
a Marca Pereira, Luz Maria
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BMI1 Drives Steroidogenesis Through Epigenetically Repressing the p38 MAPK Pathway
Frontiers in Cell and Developmental Biology, 2021 Testosterone biosynthesis progressively decreases in aging males primarily as a result of functional changes to Leydig cells. Despite this, the mechanisms underlying steroidogenesis remain largely unclear.
Jun Yu +13 more
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Bisphenol A and ovarian steroidogenesis [PDF]
Fertility and Sterility, 2016 Bisphenol A is widely used as a component in polycarbonate plastics for food and beverage packaging, epoxy linings for canned foods, and dental sealants, among other applications. Experimental literature demonstrates BPA's affinity for estrogen receptors and downstream effects on estrogen-responsive genes.
Michael S, Bloom +2 more
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The Journal of Clinical Investigation, 2022 Through their ability to regulate gene expression in most organs, glucocorticoid (GC) hormones influence numerous physiological processes and are therefore key regulators of organismal homeostasis.
Vijay K. Yadav +4 more
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