Results 31 to 40 of about 38,975 (250)

In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses

Poultry Science, 2022
: Corticosterone is critical for the maturation and survival of chicken fetus around hatching. Betaine is used as a feed additive in poultry industry to promote growth and mitigate stress.
Halima Abobaker, Nagmeldin A. Omer, Yun Hu, Abdulrahman A. Idriss, Ruqian Zhao   +4 more
doaj   +1 more source

Estimation of the Mechanism of Adrenal Action of Endocrine-Disrupting Compounds Using a Computational Model of Adrenal Steroidogenesis in NCI-H295R Cells

Journal of Toxicology, 2016
Adrenal toxicity is one of the major concerns in drug development. To quantitatively understand the effect of endocrine-active compounds on adrenal steroidogenesis and to assess the human adrenal toxicity of novel pharmaceutical drugs, we developed a ...
Ryuta Saito, Natsuko Terasaki, Makoto Yamazaki, Naoya Masutomi, Naohisa Tsutsui, Masahiro Okamoto   +5 more
doaj   +1 more source

Upregulation of Low-Density Lipoprotein Receptor of the Steroidogenesis Pathway in the Cumulus Cells Is Associated with the Maturation of Oocytes and Achievement of Pregnancy

Cells, 2021
The maturation of the oocyte is influenced by cumulus cells (CCs) and associated with pregnancy rate, whereas the influencing factors have not been completely elucidated in the CCs.
Myung Joo Kim, Young Sang Kim, Yu Jin Kim, Hye Ran Lee, Kyoung Hee Choi, Eun A Park, Ki Ye Kang, Tae Ki Yoon, Sohyun Hwang, Jung Jae Ko, You Shin Kim, Jae Ho Lee   +11 more
doaj   +1 more source

MOESM1 of Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies [PDF]

, 2018
Additional file 1.
O'Hara, Laura, O’hara, Laura; id_orcid, Tom Freeman (3440), O’shaughnessy, Peter J., Laura O’Hara (5141273), Lee B. Smith, Peter O’Shaughnessy (4845118), Laura O’Hara, Tom C. Freeman, Freeman, TC, Smith, LB, Peter J. O’Shaughnessy, O'Shaughnessy, Peter J., Lee Smith (59284), O'Shaughnessy, PJ, Freeman, Tom C., Smith, Lee B., O'Hara, L   +17 more
core   +1 more source

IGF2 increases de novo steroidogenesis in prostate cancer cells

, 2013
Free to read\ud \ud Androgen-dependent pathways regulate maintenance and growth of normal and malignant prostate tissues. Androgen deprivation therapy (ADT) exploits this dependence and is used to treat metastatic prostate cancer; however, regression ...
Hollier, Brett G., Gleave, Martin, Fazli, Ladan, Herington, Adrian, Hendy, Stephen C., Pollak, Michael N., Lubik, Amy, Gunter, Jennifer, Ettinger, Susan, Stylianou, Nataly, Adomat, Hans, Nelson, Colleen C.   +11 more
core   +1 more source

Melatonin Regulates the Synthesis of Steroid Hormones on Male Reproduction: A Review

Molecules, 2018
Melatonin is a ubiquitous molecule and exhibits different effects in long-day and short-day breeding animals. Testosterone, the main resource of androgens in the testis, is produced by Leydig cells but regulated mainly by cytokine secreted by Sertoli ...
Kun Yu, Shou-Long Deng, Tie-Cheng Sun, Yuan-Yuan Li, Yi-Xun Liu   +4 more
doaj   +1 more source

The anti-epileptic drug Valproic Acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro

, 2012
Valproic acid (VPA) is used widely to treat epilepsy and bipolar disorder. Women undergoing VPA treatment reportedly have an increased incidence of polycystic ovarian syndrome (PCOS)-like symptoms including hyperandrogenism and oligo- or amenorrhoea.
Knight, PG, Michael Anthony E., Leanne Satchell, Glister, C, Philip G Knight, Michael, AE, Satchell, Leanne, Satchell, L, Knight Philip G., Bicknell, Andrew B., Anthony E Michael, Knight, Philip G., Satchell Leanne, Glister, Claire, Andrew B Bicknell, Michael, Anthony E., Bicknell, AB, Glister Claire, Claire Glister, Bicknell Andrew B.   +19 more
core   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Concerns with Male Infertility Induced by Exposure to Titanium Nanoparticles and the Supporting Impact of Pelargonium graveolens Essential Oil: Morphometric Records in Male-Wistar Rats

Life, 2022
Background: Due to the increased use of titanium dioxide nanoparticles (TiO2 NPs), the risks of their reprotoxic effect arise. This study anticipated examining the potential protective effects of GEO (geranium essential oil) components screened via GC/MS
Ahmed Abdou Said, Yasmin Nasr, Azza A. A. Galal, Ahmed E. Abdelhamid, Haiam A. Mohamed, Mohamed M. M. Metwally, Mahmoud A. Said, Mohamed A. Nassan, Naief Dahran, Amany Abdel-Rahman Mohamed   +9 more
doaj   +1 more source

Insulin increases De Novo Steroidogenesis in prostate cancer cells

, 2011
Androgen-dependent pathways regulate maintenance and growth of normal and malignant prostate tissues. Androgen deprivation therapy (ADT) exploits this dependence and is used to treat metastatic prostate cancer; however, regression initially seen with ADT
Herington, Adrian, Vanessa Thompson, Jennifer A. Locke, Adrian Herington, Colleen C. Nelson, Martin E. Gleave, Adomat, Hans, Pollak, Michael, Nelson, Colleen, Hans H. Adomat, Amy A. Lubik, Locke, Jennifer, Gleave, Martin, Jennifer H. Gunter, Stephen C. Hendy, Lubik, Amy, Gunter, Jennifer, Michael Pollak, Thompson, Vanessa, Hendy, Stephen   +19 more
core   +1 more source