Results 171 to 180 of about 650,508 (231)

The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli   +3 more
wiley   +1 more source

Human and mouse adrenal glands are characterized by species-specific steroidogenic states and tissue turnover. [PDF]

open access: yesNat Genet
Kastriti ME   +29 more
europepmc   +1 more source

Parent child contact problems—Re‐connecting the dots through a somatic lens

open access: yesFamily Court Review, Volume 64, Issue 4, Page 767-786, October 2026.
Abstract Parent child contact problems (PCCP) and parental alienation (PA) occupy much time for family law professionals especially as parents might use the term PA loosely, for the parent allegedly doing PA and the parent experiencing PA. Negotiating safety, connection and distance are fundamental to PCCP.
Maureen Mueller
wiley   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

open access: yesThe FEBS Journal, Volume 293, Issue 20, Page 5996-6010, October 2026.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger   +3 more
wiley   +1 more source

Chronic Pre‐Trauma Corticosterone Attenuates Trauma Memory Formation and Alters Gene Expression in Glucocorticoid Signalling Pathways

open access: yesGenes, Brain and Behavior, Volume 25, Issue 5, October 2026.
The graphical abstract outlines the experimental workflow and key findings, showing how chronic or acute corticosterone elevations alter FC‐induced molecular and behavioural changes during trauma memory formation, consolidation, and recall. Abbreviations: Cort.—Corticosterone; FC—Fear Conditioning; PRPs—Plasticity‐Related Proteins.
Gia Kutelia   +6 more
wiley   +1 more source

Multimodal Neuroimaging and Behavioral Characterization of Aged Female APOE4 Knock‐In Rats Reveals a Preclinical Alzheimer's Disease Phenotype

open access: yesGenes, Brain and Behavior, Volume 25, Issue 5, October 2026.
Voxel‐based morphometry of regional brain volumes in aged female APOE4 and APOE3 knock‐in rats. APOE4 carriers present with larger brains. ABSTRACT The apolipoprotein E ε4 allele (APOE4) is the strongest genetic risk factor for sporadic Alzheimer's disease (AD) and confers disproportionate risk in women, particularly after reproductive senescence.
Noah J. Cavallaro   +10 more
wiley   +1 more source

Prolactin receptor signalling contributes to the attenuation of stress‐induced hyperthermia during pregnancy

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract During pregnancy, thermoregulation is tightly controlled to protect the foetus from harmful elevated temperatures. Stress‐induced hyperthermia is a component of the stress response that increases alertness to a perceived threat. Previous literature has shown that like other aspects of the stress response, stress‐induced hyperthermia is ...
Andrew M. Stewart   +2 more
wiley   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

open access: yesThe Journal of Physiology, Volume 604, Issue 20, Page 8323-8344, 15 October 2026.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

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