Results 151 to 160 of about 30,498 (245)

Adrenal crisis in a patient with APS2 due to COVID-19: A case report. [PDF]

open access: yesJ Family Med Prim Care, 2022
Suryadevara V   +5 more
europepmc   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

1. Physiopathology of Adrenal Crisis

open access: yesNihon Naika Gakkai Zasshi, 2008
Tetsuya Suwa, Tomoatsu Mune
openaire   +2 more sources

Nervonic acid, a long chain monounsaturated fatty acid, improves mitochondrial function in adrenomyeloneuropathy fibroblasts

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Nervonic acid plays a vital role in maintaining normal brain and neuronal function. Nervonic acid has gained increasing attention because of its potential neuroprotective and anti‐inflammatory properties. Nonetheless, the beneficial effects of nervonic acid are yet to be fully investigated. Adrenomyeloneuropathy (AMN), a
Chenxu Li   +2 more
wiley   +1 more source

Advancing antihypertensive drug development

open access: yesBritish Journal of Pharmacology, EarlyView.
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu   +5 more
wiley   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

open access: yesBritish Journal of Pharmacology, EarlyView.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio   +5 more
wiley   +1 more source

Cytological Assessment of Adrenal Tumours: Insights From 22‐Years Single Centre Experience

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective The incidence of adrenal tumours has increased in the last decades, mainly due to increased use of imaging. The diagnostic evaluation of adrenal masses can be complex and, in some cases, necessitates cytological evaluation. However, concerns remain regarding the potential complications associated with adrenal gland biopsy.
Ana Carasel   +3 more
wiley   +1 more source

Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost‐Effectiveness Perspective

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Patients require additional treatment when pituitary surgery for Cushing's disease is unsuccessful. Exciting innovations in pituitary surgery bring hope for achieving better outcomes. Quantifying the potential value of these innovations using early health economic modelling can provide guidance throughout their development.
Femke J. C. Jacobs   +4 more
wiley   +1 more source

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