Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 Oxidoreductase deficiency [PDF]
, 2010 Context: P450 oxidoreductase (POR) is a crucial electron donor to all microsomal P450 cytochrome (CYP) enzymes including 17α-hydroxylase (CYP17A1), 21-hydroxylase (CYP21A2) and P450 aromatase.
Adachi +59 more
core +2 more sources
Work-Related Stress, Physio-Pathological Mechanisms, and the Influence of Environmental Genetic Factors [PDF]
, 2019 Work-related stress is a growing health problem in modern society. The stress response is characterized by numerous neurochemicals, neuroendocrine and immune modifications that involve various neurological systems and circuits, and regulation of the gene
Emanuele Cannizzaro +3 more
core +1 more source
Growth Patterns in the First Three Years of Life in Children with Classical Congenital Adrenal Hyperplasia Diagnosed by Newborn Screening and Treated with Low Doses of Hydrocortisone [PDF]
, 2011 Background: Linear growth is the best clinical parameter for monitoring metabolic control in classical congenital adrenal hyperplasia (CAH). Objective: To analyze growth patterns in children with CAH diagnosed by newborn screening and treated with ...
Bonfig, W., Schmidt, H., Schwarz, H. P.
core +1 more source
A Case of Adrenal Crisis-Induced Stress Cardiomyopathy
Cureus, 2021 We report a case of a 36-year-old male who presented to the emergency department with complaints of weakness. On presentation the patient was hypotensive, hyperkalemic, and hyponatremic.
C. Harris +4 more
semanticscholar +1 more source
New directions for the treatment of adrenal insufficiency [PDF]
, 2015 The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen +69 more
core +5 more sources
European Heart Journal: Case Reports, 2021 Background Adrenal crisis is an acute life-threatening exacerbation of the Addison’s disease or primary adrenal insufficiency (PAI) and is associated with a high mortality rate.
E. Lüsebrink +3 more
semanticscholar +1 more source
Rare Bilateral Adrenal Haemorrhage with Addisonian Crisis: When Risk Factors Come in Droves
Case Reports in Endocrinology, 2020 Addisonian crisis is the life-threatening acute manifestation of adrenal insufficiency due to absolute or relative glucocorticoid deficiency. Adrenal haemorrhage is a rare condition of unknown incidence with the risk of adrenal insufficiency and death ...
Anders Boisen Jensen +2 more
doaj +1 more source
Bilateral adrenal haemorrhage leading to adrenal crisis [PDF]
BMJ Case Reports, 2014 A 77-year-old man presented with an acute worsening of chronic back pain. CT showed dense bilateral adrenal glands suggestive of adrenalhaemorrhagewhich was confirmed by MRI. Despite appropriate glucocorticoid replacement for adrenal insufficiency, 7 days after admission this patient suffered an adrenal crisis.
openaire +2 more sources
Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
, 2019 Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G +6 more
core +2 more sources
Journal of Medical Case Reports, 2021 Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis.
Abere Genetu +4 more
semanticscholar +1 more source