Results 31 to 40 of about 102,920 (238)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Untreated Congenital Adrenal Hyperplasia with 17-α Hydroxylase/17,20-Lyase Deficiency Presenting as Massive Adrenocortical Tumor [PDF]

Endocrinology and Metabolism, 2015
Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase/17,20-lyase deficiency is usually characterized by hypertension and primary amenorrhea, sexual infantilism in women, and pseudohermaphroditism in men. hypertension, and sexual infantilism in women
Su Jin Lee, Je Eun Song, Sena Hwang, Ji-Yeon Lee, Hye-Sun Park, Seunghee Han, Yumie Rhee   +6 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

An exceedingly rare adrenal collision tumor: adrenal adenoma–metastatic breast cancer–myelolipoma

Journal of Community Hospital Internal Medicine Perspectives, 2017
Adrenal collision tumors (ACTs), in which distinct tumors coexist without histological intermingling in the same adrenal gland, are rare and their actual prevalence is unknown. ACTs commonly consist of adrenal cortical adenoma, myelolipoma, or metastatic
Dongyan Liu, Sahayini A. Kumar
doaj   +1 more source

A Giant Solitary Adrenal Plasmacytoma in a Patient with HIV: A Rare Case Report and Review of the Literature

Case Reports in Urology, 2021
Solitary extramedullary plasmacytoma (EMP) involving the adrenal gland is an extremely rare malignancy. We report a case of a solitary adrenal plasmacytoma in an HIV-positive 50-year-old woman on antiretroviral therapy who presented with a rapidly ...
Mehdi Chennoufi, Ibrahim Boukhannous, Mohamed Mokhtari, Anouar El Moudane, Mohamed Irzi, Abdelghani Ouraghi, Issam Jandou, Achraf Miry, Ali Barki   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

IS COMPUTERIZED TOMOGRAPHY RELIABLE FOR DETECTING TUMOR NUMBER AND ADRENAL GLAND INVOLVEMENT IN PATIENTS WITH RENAL CELL CANCER? A MULTICENTER STUDY

Urology Research and Practice, 2019
Introduction: Renal cell cancer (RCC) represents the fifth most common cancer in men, with a rising incidence. Computerized tomography (CT) remains the most appropriate imaging modality to diagnose renal malignancies.
Aves Editorial Aves Editorial
doaj   +2 more sources

Recurrent fever leading to the diagnosis of an angiosarcoma of the adrenal gland: a case report

Journal of Medical Case Reports
Background Angiosarcoma of the adrenal gland is a very rare malignant vascular neoplasm. The clinical symptoms are atypical or completely absent. Angiosarcomas of the adrenal gland are therefore often discovered incidentally, and the diagnosis is made ...
Ann-Kathrin Lederer, Stefanie Zimmer, Rabea Margies, Philipp Krettek, Thomas J. Musholt   +4 more
doaj   +1 more source

COMPARAÇÃO DAS CARACTERÍSTICAS E MEDIDAS ULTRASSONOGRÁFICAS DAS GLÂNDULAS ADRENAIS DE CÃES E GATOS FILHOTES SAUDÁVEIS

Ciência Animal Brasileira, 2013
The aim of the study was to analyze and compare the ultrasound characteristics of adrenal glands between healthy puppies and kittens by establishing standards of normality and references.
Ivan F. Charas Santos, Maria Jaqueline Mamprim, Raquel Sartor   +2 more
doaj   +1 more source