Results 121 to 130 of about 37,949 (281)
Adrenal Glands - The Current Stage and New Perspectives of Diseases and Treatment [PDF]
Diana Păun+28 more
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Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin+8 more
wiley +1 more source
A Case of Myelolipoma of the Adrenal Gland with Close Examination of other Disease.
Akihiro Naito+4 more
openalex +2 more sources
Increased expression of proopiomelanocortin (POMC) mRNA in adrenal glands of mice undergoing graft-versus-host disease (GVHD); association with persistent elevated plasma corticosterone levels [PDF]
Kong Eric You-Ten+4 more
openalex +1 more source
Pregnenolone Reduces L‐Dopa‐Induced Dyskinesias in Female Parkinsonian Monkeys
Pregnenolone is the first neurosteroid synthesized from cholesterol in the brain. Ovariectomized female monkeys were tested as a model of women in menopause. They were lesioned with MPTP modeling Parkinson's disease and treated with levodopa (L‐dopa) to induce dyskinesias.
Mélanie Bourque+5 more
wiley +1 more source
The Adrenal Gland: Common Disease States and Suspected New Applications [PDF]
Linda S. Gorman
openalex +1 more source