Results 171 to 180 of about 241,535 (385)

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Research Methodology in Acupuncture for Managing Interstitial Cystitis/Bladder Pain Syndrome: A Scoping Review

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Background Acupuncture and moxibustion are being explored as complementary therapies with promising potential in managing interstitial cystitis/bladder pain syndrome (IC/BPS). While some studies indicate possible benefits, their scientific basis and clinical efficacy remain subjects of debate, partly due to methodological flaws in study ...
Miguel Ángel Infantes Rosales   +3 more
wiley   +1 more source

Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization

open access: yesThe Journal of Pathology, EarlyView.
Abstract Mucinous cystic neoplasms (MCNs) of the pancreas are macroscopic precursors of pancreatic cancer. A similar cystic lesion but lacking the ovarian‐type subepithelial stroma has been recently defined as a simple mucinous cyst (SMC); however, its nature remains unclear. This study aims to define the clinicopathological and molecular profiles of a
Antonio Pea   +37 more
wiley   +1 more source

A Novel Use of Pseudospectra in Mathematical Biology: Understanding HPA Axis Sensitivity [PDF]

open access: yesarXiv
The Hypothalamic-Pituitary-Adrenal (HPA) axis is a major neuroendocrine system, and its dysregulation is implicated in various diseases. This system also presents interesting mathematical challenges for modeling. We consider a nonlinear delay differential equation model and calculate pseudospectra of three different linearizations: a time-dependent ...
arxiv  

Wilms Tumor in Children with AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 10–15% of children with Wilms tumor (WT) have predisposing genetic syndromes. Somatic mutations are frequently identified; however, germline pathogenic variants in AMER1 are much less prevalent and are associated with osteopathia striata with cranial sclerosis (OSCS).
Insiyah Campwala   +9 more
wiley   +1 more source

Outcomes after Surgical Treatment of Metastatic Disease in the Adrenal Gland; Valuable for the Patient? [PDF]

open access: gold, 2021
Madelon J. H. Metman   +9 more
openalex   +1 more source

Comprehensive Review of the Impact of Maternal Stress on Fetal Development

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Maternal stress impacts millions of pregnant women across the globe each year and refers to mental or psychological stress that occurs during the prenatal period. Although it remains known that maternal stress can negatively impact maternal health, the downstream effects of stress on fetal and infant development in the long‐term are unclear ...
Divya Tadanki   +8 more
wiley   +1 more source

Tratamento cirúrgico da hipertensão arterial secundária com origem na glândula supra-renal

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Among the main etiologies of secondary arterial hypertension figure out the tumorous affections of adrenal gland, located on cortex - primary aldosteronism (Conn’s syndrome) and Cushing’s syndrome - or at glandular medulla - pheocromocytoma.
Ruy Garcia Marques   +1 more
doaj   +1 more source

Identification of Prognostic Biomarkers in Gene Expression Profile of Neuroblastoma Via Machine Learning

open access: yesPediatric Discovery, EarlyView.
This study identified 11 core prognostic biomarkers for neuroblastoma through optimized PPI networks and machine learning, revealing their correlations with chemotherapy and the tumor microenvironment, providing new insights for precision treatment and target development.
Shuxin Tang, Jinhua Fan, Yupeng Cun
wiley   +1 more source

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