Results 191 to 200 of about 245,104 (332)

Refining Tumor Mutational Burden as a Predictive Biomarker for Pembrolizumab: A Real‐World Analysis in Japanese Patients

Cancer Science, EarlyView.
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda, Mio Yumura, Azusa Hamasaki, Tongyi Fei, Takashi Kubo, Hitoshi Ichikawa, Takashi Kohno, Kuniko Sunami   +7 more
wiley   +1 more source

Cerebrovascular Function in Women With Polycystic Ovary Syndrome: A Pilot Multi‐Parameter Magnetic Resonance Imaging Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is associated with an increased risk of cerebrovascular disease, but the effects on cerebrovascular function are unknown. In this pilot study, we sought to compare cerebrovascular perfusion, pulsatility, reactivity and metabolism between women with PCOS and healthy volunteers using MRI, and ...
Melissa E. Wright, Cory T. Richards, Saajan Davies, Rachel N. Lord, D. Aled Rees, Kevin Murphy   +5 more
wiley   +1 more source

Disseminated cryptococcosis involving the adrenal gland and brain in an immunocompetent patient: A case report. [PDF]

Medicine (Baltimore)
Rao Q, Wu F, Su D, Song X, Su J, Ma L, Xu J, Fan S, Zhu J, Wen J.   +9 more
europepmc   +1 more source

Changes in morphology and function of adrenal cortex in mice fed a high-fat diet

International Journal of Obesity, 2014
Marta M. Swierczynska, Ivona Mateska, M. Peitzsch, S. R. Bornstein, Trian Chavakis, G. Eisenhofer, V. Lamounier-zepter, Suzanne Eaton   +7 more
semanticscholar   +1 more source

University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students

Clinical Endocrinology, EarlyView.
ABSTRACT Background University exams are recognised as naturalistic stressors that may elicit psychosocial and physiological responses in students. This pilot study investigated the short‐ and long‐term effects of exam‐related stress on hypothalamic–pituitary–adrenal (HPA) axis activity, focusing on cortisol production and rhythmicity.
Filipy Borghi, Priscila Cristina da Silva, Elisângela Farias‐Silva, Fernando Canova, Aglecio Luiz Souza, Aline Barbedo Arouca, Dora Maria Grassi   +6 more
wiley   +1 more source

Hemorrhage or thrombosis? Adrenal involvements in a patient with antiphospholipid syndrome. [PDF]

Rheumatol Immunol Res
Liu L, Wang Q, Jiang Y, Huang C.
europepmc   +1 more source

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary, Dinushan Raveendran, Ramesh Nair, Aimee Di Marco, Debbie Papadopoulou, Florian Wernig, Ali Abbara, Karim Meeran, Niamh Martin, Jeremy Cox, Alexander N. Comninos   +10 more
wiley   +1 more source

ACTH Stimulation Testing Is Often Unnecessary After Appropriate Patient Preparation Prior to Screening Cortisol Measurement

Clinical Endocrinology, EarlyView.
ABSTRACT Context Screening morning serum cortisol is used to select patients for ACTH stimulation testing to diagnose adrenal insufficiency (AI) but may be affected by pre‐analytical factors. Careful consideration to discontinue confounding medications beforehand may preclude the need for subsequent stimulation testing.
Christopher J. Symonds, Alexander A. Leung, Gregory A. Kline   +2 more
wiley   +1 more source

Perspectives on Adrenal Tumor Surgery. [PDF]

Medicina (Kaunas)
Baston C, Parosanu A, Moldoveanu O, Discalicău L, Visinescu P, Precup A, Sinescu I.   +6 more
europepmc   +1 more source

Ultrasonographic appearance of adrenal glands in healthy and sick cats

Journal of feline medicine and surgery, 2013
A. Combes, P. Pey, D. Paepe, D. Rosenberg, S. Daminet, I. Putcuyps, A. Bedu, L. Duchateau, P. de Fornel-Thibaud, G. Benchekroun, J. Saunders   +10 more
semanticscholar   +1 more source