Results 141 to 150 of about 18,302 (321)

3D Deep-learning-based Segmentation of Human Skin Sweat Glands and Their 3D Morphological Response to Temperature Variations [PDF]

arXiv
Skin, the primary regulator of heat exchange, relies on sweat glands for thermoregulation. Alterations in sweat gland morphology play a crucial role in various pathological conditions and clinical diagnoses. Current methods for observing sweat gland morphology are limited by their two-dimensional, in vitro, and destructive nature, underscoring the ...
arxiv  

[Current indications for video-laparoscopic surgery of adrenal gland neoplasms].

Il Giornale di chirurgia, 1997
Recent advances in pathophysiology of the adrenal glands suggest new indications for adrenalectomy. In open surgery large incisions are needed to remove a small gland; on the contrary, laparoscopic procedures offer new possibilities. The present study is a review of the literature on indications, contraindications and surgical technique of laparoscopic
L, Angrisani, U A, Bassi, G, Roina, O, Nicodemi, T, Santoro, B, Tesauro   +5 more
openaire   +1 more source

Gland Segmentation Using SAM With Cancer Grade as a Prompt [PDF]

arXiv
Cancer grade is a critical clinical criterion that can be used to determine the degree of cancer malignancy. Revealing the condition of the glands, a precise gland segmentation can assist in a more effective cancer grade classification. In machine learning, binary classification information about glands (i.e., benign and malignant) can be utilized as a
arxiv  

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Indications for laparoscopic adrenalectomy as a determinant of the perioperative and postoperative course: a retrospective, single-centre cohort study

Studia Medyczne, 2023
Łukasz Niedziela, Emilia Niedziela, Mateusz Obarzanowski, Paweł Orłowski, Marcin Kosowski, Aldona Kowalska, Stanisław Góźdź, Jarosław Jaskulski   +7 more
doaj   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Pancreatic resection for metachronous colorectal cancer metastases: a case series multicenter study

ANZ Journal of Surgery, EarlyView.
Abstract Background Pancreas resection for metachronous colorectal cancer metastasis is episodic and the role of surgery in the management of these patients is still debated. Methods We recruited seven patients from three different centres and analyzed 30‐day morbidity and mortality, oncological outcomes at 6 and 12 months.
Francesco Palmieri, Francesco Lancellotti, Francesco Ferrara, Thomas Satyadas, Davide Gobatti, Luis Felipe Abreu de Carvalho, Filip Gryspeerdt, Grazia Conte, Federico Mocchegiani, Roberto Sampietro, Pierpaolo Sileri   +10 more
wiley   +1 more source

Impact of MYD88 and/or CD79B mutations on central nervous system relapse in patients with diffuse large B‐cell lymphoma

British Journal of Haematology, EarlyView.
This study examined the effect of MYD88L265P (myeloid differentiation primary response gene 88 mutation L265P) and/or CD79BY196 (cluster of differentiation 79B gene mutation Y196) on central nervous system (CNS) relapse in 270 patients with newly diagnosed diffuse large B‐cell lymphoma.
Tomotaka Suzuki, Keiichiro Fujii, Naohiro Matsunaga, Hirokazu Sasaki, Takashi Kanamori, Arisa Asano, Shiori Kinoshita, Tomoko Narita, Ayako Masaki, Takaomi Sanda, Masaki Ri, Shigeru Kusumoto, Hirokazu Komatsu, Shinsuke Iida, Hiroshi Inagaki   +14 more
wiley   +1 more source

Validation of target‐enriched enzymatic methylation sequencing for brain tumor classification from formalin‐fixed paraffin embedded‐derived DNA

Brain Pathology, EarlyView.
Target‐enriched enzymatic methylation sequencing (TEEM‐seq), a DNA methylation sequencing method using the Twist Human Methylome panel, shows comparable performance to array‐based tumor methylation profiling. The method is compatible with both frozen and formalin‐fixed paraffin‐embedded (FFPE) samples and is a viable approach to tumor methylation and ...
Quynh T. Tran, Sujuan Jia, Md. Zahangir Alom, Lu Wang, Charles G. Mullighan, Ruth G. Tatevossian, Brent A. Orr   +6 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source