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Enlightening the adrenal gland [PDF]
Cell Metabolism, 2005 The secretion of glucocorticoid hormones is tightly regulated by the circadian clock and by negative humoral feedback loops, both acting on the hypothalamic-pituitary gland-adrenal axis. However, a new study Ishida et al., 2005 [this issue of Cell Metabolism) shows that light can influence the adrenal's glucocorticoid output by a more direct pathway.
Steven A. Brown +2 more
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Disease of Adrenal Glands [PDF]
International Journal of Endocrinology, 2015 The adrenal gland has been historically an object of interest and scientific curiosity. This is also due to its very heterogeneous structure, number of hormones, complex neural innervation, and multiple and different physiological functions.
Gianluca Iacobellis +3 more
openaire +4 more sources
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19 [PDF]
, 2022 Progressive respiratory failure and hyperinflammatory response is the primary cause of death in the coronavirus disease 2019 (COVID-19) pandemic. Despite mounting evidence of disruption of the hypothalamus-pituitary-adrenal axis in COVID-19, relatively ...
Bartsch, Harald +23 more
core +1 more source
Sexual Differentiation of Circadian Clock Function in the Adrenal Gland [PDF]
, 2016 Sex differences in glucocorticoid production are associated with increased responsiveness of the adrenal gland in females. However, the adrenal-intrinsic mechanisms that establish sexual dimorphic function remain ill defined. Glucocorticoid production is
Evans, Jennifer A. +5 more
core +2 more sources
Primary bilateral non-Hodgkin’s lymphoma of the adrenal gland presenting as incidental adrenal masses [PDF]
, 2015 Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease.
Betts, Alexandra +4 more
core +4 more sources
Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland [PDF]
, 2011 The melanocortin-2-receptor (MC2R)/MC2R accessory protein (MRAP) complex is critical to the production of glucocorticoids from the adrenal cortex. Inactivating mutations in either MC2R or MRAP result in the clinical condition familial glucocorticoid ...
Chan, LF +4 more
core +2 more sources
Persistent isolated hypocortisolism following brief treatment with trilostane [PDF]
, 2008 A 12-year-old male neutered Miniature Poodle with confirmed pituitary-dependent hyperadrenocorticism was treated with trilostane. After three doses, it developed clinical and laboratory changes suggestive of isolated hypocortisolism ('atypical ...
Barker +19 more
core +1 more source
Label-free enrichment of adrenal cortical progenitor cells using inertial microfluidics. [PDF]
, 2012 Passive and label-free isolation of viable target cells based on intrinsic biophysical cellular properties would allow for cost savings in applications where molecular biomarkers are known as well as potentially enable the separation of cells with little-
Brinckerhoff, Tatiana Z +4 more
core +2 more sources
Journal of the Belgian Society of Radiology, 2011 A 22-year old female was referred to our hospital for CT-evaluation of the abdomen. Her medical history revealed a congenital lumbosacral spina bifida with meningomyelocele, which was surgically closed at the age of 22 months. She had a neurogenic bladder with hydronephrosis of the right kidney and recurrent upper urinary tract infections.
E Schollaert +2 more
openaire +5 more sources
Contribution of the adrenal gland to the production of androstenedione and testosterone during the first two years of life [PDF]
, 1986 Androstenedione and testosterone were measured in whole adrenal glands of 56 previously healthy boys who died suddenly between birth and 2 yr of age. In each adrenal gland, the concentration of androstenedione considerably exceeded that of testosterone ...
Bidlingmaier, F. +4 more
core +1 more source