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CYP2W1 is highly expressed in adrenal glands and is positively associated with the response to mitotane in adrenocortical carcinoma. [PDF]

open access: yesPLoS ONE, 2014
Adrenocortical tumors comprise frequent adenomas (ACA) and rare carcinomas (ACC). Human cytochrome P450 2W1 (CYP2W1) is highly expressed in some cancers holding the potential to activate certain drugs into tumor cytotoxins.To investigate the CYP2W1 ...
Cristina L Ronchi   +12 more
doaj   +2 more sources

A spatiotemporal steroidogenic regulatory network in human fetal adrenal glands and gonads [PDF]

open access: yesFrontiers in Endocrinology, 2022
Human fetal adrenal glands produce substantial amounts of dehydroepiandrosterone (DHEA), which is one of the most important precursors of sex hormones. However, the underlying biological mechanism remains largely unknown. Herein, we sequenced human fetal
Yifu Wang   +93 more
doaj   +2 more sources

Age-related morphometrics of normal adrenal glands based on deep learning-aided segmentation [PDF]

open access: yesHeliyon, 2023
Objective.This study aims to evaluate the morphometrics of normal adrenal glands in adult patients semiautomatically using a deep learning-based segmentation model.Materials and Methods.A total of 520 abdominal CT image series with normal findings, from ...
Yuanchong Chen   +5 more
doaj   +2 more sources

Computed Tomography Volumetric Measurements of Adrenal Glands in 26 Dogs Under One Year of Age: A Retrospective Study [PDF]

open access: yesVeterinary Sciences
Limited data exist regarding the size and volume of adrenal glands in puppies; therefore, the present research aims to describe volumetric and traditional measurements of adrenal glands in computed tomography (CT) images of 26 dogs under 1 year of age ...
Julia Topmöller   +5 more
doaj   +2 more sources

Prospective Ultrasonographic Evaluation of Adrenal Glands in a Population of Beagle Puppies and Functional Analysis of Basal Cortisol Levels in Blood [PDF]

open access: yesVeterinary Sciences
This study presents a prospective evaluation of adrenal gland development in a cohort of Beagle puppies, utilizing sonographic imaging and functional assessment of the basal serum cortisol concentrations.
Julia Topmöller   +5 more
doaj   +2 more sources

Adrenal glands in normal and anomalous foetuses - a comparative study

open access: greenNational Journal of Clinical Anatomy, 2017
Background and aim: Foetal adrenal gland is an important factor which determines neonatal survival. Adrenal hypoplasia can result in respiratory distress and neonatal death.
C Manju Madhavan
doaj   +2 more sources

CT Anatomical Features and Dimensions of the Rabbit Adrenal Glands [PDF]

open access: yesVeterinary Sciences
Background: Adrenal glands are situated cranially and in close proximity to both kidneys. The rabbit is a preferred animal pet species and is also used as an experimental model in research.
Kamelia Stamatova-Yovcheva   +7 more
doaj   +2 more sources

Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses [PDF]

open access: yesCase Reports in Medicine, 2015
Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease.
Christopher Rizzo   +4 more
doaj   +5 more sources

Comparative morphological and morphometrically study of the adrenal gland in adult males' squirrel (Sciurus anomalous) and hamster (Mesocricetus auratus) [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2022
Given the physiological significance and the need for further physiological and morphological knowledge of the adrenal glands, the objectives of the current study were to compare morphometric data between the right and left adrenals of male squirrels and
ِAbdulrazzaq B. Kadhim, Iman M. Khaleel
doaj   +1 more source

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