Results 51 to 60 of about 748,383 (382)

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

A deep learning algorithm for automated adrenal gland segmentation on non-contrast CT images

BMC Medical Imaging
Background The adrenal glands are small retroperitoneal organs, few reference standards exist for adrenal CT measurements in clinical practice. This study aims to develop a deep learning (DL) model for automated adrenal gland segmentation on non-contrast
Fanxing Meng, Tuo Zhang, Yukun Pan, Xiaojing Kan, Yuwei Xia, Mengyuan Xu, Jin Cai, Fangbin Liu, Yinghui Ge   +8 more
doaj   +1 more source

Radiological Imaging Findings of Adrenal Abnormalities in TAFRO Syndrome: A Systematic Review

Biomedicines
This systematic review article aims to investigate the clinical and radiological imaging characteristics of adrenal abnormalities in patients with thrombocytopenia, anasarca, fever, reticulin fibrosis, renal dysfunction, and organomegaly (TAFRO) syndrome.
Ryo Kurokawa, Akira Baba, Rui Kano, Yo Kaneko, Mariko Kurokawa, Wataru Gonoi, Osamu Abe   +6 more
doaj   +1 more source

Chrysin’s dose-dependent effects on steroidogenesis in female BALB/c mice: In vivo study of adrenal, ovarian, and uterine hormone regulation [PDF]

Pharmacia
Background: Chrysin is known for its pharmacological effects and structural resemblance to estrogen. The study explores the impact of chrysin on steroidogenesis focusing on adrenal and ovarian steroidogenic enzymes.
Khalid M. Alqaisi, Manal A. Abbas, Rand Alshawawreh   +2 more
doaj   +3 more sources

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Stability analysis of a hypothalamic-pituitary-adrenal axis model with inclusion of glucocorticoid receptor and memory

, 2016
This paper analyzes a four-dimensional model of the hypothalamic-pituitary-adrenal (HPA) axis that includes the influence of the glucocorticoid receptor in the pituitary.
Kaslik, Eva, Navolan, Dan Bogdan, Neamtu, Mihaela   +2 more
core   +1 more source

Computational Analysis of a GST‐Based Long‐Wave Infrared Microring Resonator on a ZnSe Platform as a Photonic Sensor

Advanced Photonics Research, EarlyView.
A Ge2Sb2Te5 (GST)‐based microring resonator is designed and simulated on a ZnSe‐platform that operates in the long‐wave infrared (LWIR) wavelength of 8 μm. The structure demonstrates strong power confinement and high Q‐factor. GST resonator is used for gas and biosensing applications.
Tanzina Rahman, Md. Islahur Rahman Ebon, Amrita Kumar Sana, Jaker Hossain   +3 more
wiley   +1 more source

Neuroma embryonic sympathetic - Neuroblastoma. Review of the literature

Journal of Education, Health and Sport, 2017
Embryonic Neuroma sympathetic is derived from nerve cells, of which during normal development are sympathetic ganglia and the adrenal Medulla. Primary outbreak is found for this reason along the axis of the body - in the pelvis, retroperitoneal, bone ...
Agnieszka Budny, Jakub Litak, Cezary Grochowski   +2 more
doaj   +3 more sources

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source