Results 61 to 70 of about 32,928 (226)

GNAS mutation is an unusual cause of primary adrenal insufficiency: a case report

BMC Pediatrics, 2022
Background Primary adrenal insufficiency in children has non-specific and extensive clinical features, so the diagnosis of its etiology is complex and challenging.
Yajie Tong, Dongmei Yue, Ying Xin, Dan Zhang   +3 more
doaj   +1 more source

Adrenal Steroidogenesis and Congenital Adrenal Hyperplasia [PDF]

Endocrinology and Metabolism Clinics of North America, 2015
Adrenal steroidogenesis is a dynamic process, reliant on de novo synthesis from cholesterol, under the stimulation of ACTH and other regulators. The syntheses of mineralocorticoids (primarily aldosterone), glucocorticoids (primarily cortisol), and adrenal androgens (primarily dehydroepiandrosterone and its sulfate) occur in separate adrenal cortical ...
Richard J. Auchus, Adina F. Turcu
openaire   +3 more sources

Using behavioural network mapping to investigate dyadic play in girls with congenital adrenal hyperplasia

British Journal of Developmental Psychology, EarlyView.
Abstract Examining mechanisms underlying sex differences in children's play styles, we studied girls with congenital adrenal hyperplasia (CAH) who provide a test of the relative effects of prenatal androgens versus rearing, and of behavioural similarity versus gender identity and cognitions.
Adriene M. Beltz, Christel M. Portengen, Sheri A. Berenbaum   +2 more
wiley   +1 more source

Deep Multi-Scale Resemblance Network for the Sub-class Differentiation of Adrenal Masses on Computed Tomography Images [PDF]

arXiv, 2020
The accurate classification of mass lesions in the adrenal glands (adrenal masses), detected with computed tomography (CT), is important for diagnosis and patient management. Adrenal masses can be benign or malignant and benign masses have varying prevalence.
arxiv  

Normal sex differences in prenatal growth and abnormal prenatal growth retardation associated with 46,XY disorders of sex development are absent in newborns with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Biology of Sex Differences, 2011
Background Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is the most common presentation of a disorder of sex development (DSD) in genetic females. A report of prenatal growth retardation in cases of 46,XY DSD, coupled with observations
Chalmers Laura J, Doherty Paul, Migeon Claude J, Copeland Kenneth C, Bright Brianna C, Wisniewski Amy B   +5 more
doaj   +1 more source

Stability and Hopf bifurcation analysis for the hypothalamic-pituitary-adrenal axis model with memory [PDF]

, 2016
This paper generalizes the existing minimal model of the hypothalamic-pituitary-adrenal (HPA) axis in a realistic way, by including memory terms: distributed time delays, on one hand and fractional-order derivatives, on the other hand. The existence of a unique equilibrium point of the mathematical models is proved and a local stability analysis is ...
arxiv   +1 more source

Longitudinal Assessment of Illnesses, Stress Dosing, and Illness Sequelae in Patients With Congenital Adrenal Hyperplasia

Journal of Clinical Endocrinology and Metabolism, 2018
Context Patients with congenital adrenal hyperplasia (CAH) are at risk for life-threatening adrenal crises. Management of illness episodes aims to prevent adrenal crises. Objective We evaluated rates of illnesses and associated factors in patients with
D. El‐Maouche, Courtney J Hargreaves, N. Sinaii, A. Mallappa, P. Veeraraghavan, D. Merke   +5 more
semanticscholar   +1 more source

Increased risk of osteoporotic fractures and osteoporosis in patients with Addison's disease in Sweden: A nationwide population‐based cohort study

Journal of Internal Medicine, EarlyView.
Abstract Background The risk of major osteoporotic fractures (MOFs) and osteoporosis in patients with autoimmune Addison's disease (AAD) is unclear. Objective To investigate the risk of MOF in patients with AAD and the possible correlation with adrenal hormone replacement doses.
Stavros Stergianos, Tim Spelman, Daniel Eriksson, Sara Öster, Sigridur Björnsdottir, Olle Kämpe, Jakob Skov, Sophie Bensing   +7 more
wiley   +1 more source

Congenital Adrenal Hyperplasia: A Review of Current Knowledge and Future Directions

Quality in Sport
Introduction: Congenital adrenal hyperplasia (CAH) is a group of diseases in which genetic defects occur that disturb the synthesis of cortisol. The most common variant of CAH (95%-99%) is caused by 21-hydroxylase deficiency as a result of mutations in ...
Zuzanna Szczepaniak, Agata Konopka, Natalia Wdowiak, Karina Lissak, Małgorzata Komarów, Martyna Choinka, Dominika Karasińska, Jakub Kalisiak   +7 more
doaj   +1 more source

Stability and Hopf bifurcation analysis of a four-dimensional hypothalamic-pituitary-adrenal axis model with distributed delays [PDF]

, 2017
A four-dimensional mathematical model of the hypothalamus-pituitary-adrenal (HPA) axis is investigated, incorporating the influence of the GR concentration and general feedback functions. The inclusion of distributed time delays provides a more realistic modeling approach, since the whole past history of the variables is taken into account.
arxiv   +1 more source