Results 171 to 180 of about 79,565 (318)
Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]
Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core
ABSTRACT Background The diagnosis and management of childhood adrenal disorders is challenging. Clinical markers of hormone excess or deficiency may take months to manifest, and traditional biomarkers correlate only partially with clinical outcomes.
Julie Park+9 more
wiley +1 more source
Comparative Analysis of Pre-trained Deep Learning Models and DINOv2 for Cushing's Syndrome Diagnosis in Facial Analysis [PDF]
Cushing's syndrome is a condition caused by excessive glucocorticoid secretion from the adrenal cortex, often manifesting with moon facies and plethora, making facial data crucial for diagnosis. Previous studies have used pre-trained convolutional neural networks (CNNs) for diagnosing Cushing's syndrome using frontal facial images.
arxiv
Neurological and adrenal dysfunction in the adrenal insufficiency/alacrima/achalasia (3A) syndrome. [PDF]
David Grant+9 more
openalex +1 more source
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele+9 more
wiley +1 more source
Are physiological oscillations physiological?
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley +1 more source
CoRLD: Contrastive Representation Learning Of Deformable Shapes In Images [PDF]
Deformable shape representations, parameterized by deformations relative to a given template, have proven effective for improved image analysis tasks. However, their broader applicability is hindered by two major challenges. First, existing methods mainly rely on a known template during testing, which is impractical and limits flexibility. Second, they
arxiv
ABSTRACT Objective Patients require additional treatment when pituitary surgery for Cushing's disease is unsuccessful. Exciting innovations in pituitary surgery bring hope for achieving better outcomes. Quantifying the potential value of these innovations using early health economic modelling can provide guidance throughout their development.
Femke J. C. Jacobs+4 more
wiley +1 more source
Towards Accurate and Interpretable Neuroblastoma Diagnosis via Contrastive Multi-scale Pathological Image Analysis [PDF]
Neuroblastoma, adrenal-derived, is among the most common pediatric solid malignancies, characterized by significant clinical heterogeneity. Timely and accurate pathological diagnosis from hematoxylin and eosin-stained whole-slide images is critical for patient prognosis.
arxiv
Clinical Significance of Skeletal Fat‐to‐Muscle Ratio in Idiopathic Hyperaldosteronism
ABSTRACT Objective The objective of this study is to evaluate the correlation between the fat‐to‐muscle ratio (FMR) and insulin resistance (IR) with aldosterone production among patients with idiopathic hyperaldosteronism (IHA). Methods Patients with primary aldosteronism were screened from those with secondary hypertension and then subtyped via ...
Yuhe Jiang+6 more
wiley +1 more source