Results 221 to 230 of about 47,664 (260)
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Journal of Clinical Pathology, 2022
Adrenal insufficiency (AI), first described by Thomas Addison in 1855, is characterised by inadequate hormonal production by the adrenal gland, which could either be primary, due to destruction of the adrenal cortex, or secondary/tertiary, due to lack of adrenocorticotropic hormone or its stimulation by corticotropin-releasing hormone.
Rajeev Kumar, W S Wassif
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Adrenal insufficiency (AI), first described by Thomas Addison in 1855, is characterised by inadequate hormonal production by the adrenal gland, which could either be primary, due to destruction of the adrenal cortex, or secondary/tertiary, due to lack of adrenocorticotropic hormone or its stimulation by corticotropin-releasing hormone.
Rajeev Kumar, W S Wassif
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Journal of Surgical Oncology, 2012
AbstractAdrenocortical insufficiency may arise through primary failure of the adrenal glands or due to lack of ACTH stimulation as a result of pituitary or hypothalamic dysfunction. Prolonged administration of exogenous steroids will suppress the hypothalamic–pituitary‐adrenal axis, and hence cortisol secretion.
Melissa, Li-Ng, Laurence, Kennedy
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AbstractAdrenocortical insufficiency may arise through primary failure of the adrenal glands or due to lack of ACTH stimulation as a result of pituitary or hypothalamic dysfunction. Prolonged administration of exogenous steroids will suppress the hypothalamic–pituitary‐adrenal axis, and hence cortisol secretion.
Melissa, Li-Ng, Laurence, Kennedy
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Sepsis and Adrenal Insufficiency
Journal of Intensive Care Medicine, 2023In sepsis, dysregulation of the hypothalamic–pituitary–adrenal axis, alterations in cortisol metabolism, and tissue resistance to glucocorticoids can all result in relative adrenal insufficiency or critical illness-related corticosteroid insufficiency (CIRCI).
Cosmo Fowler +2 more
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JAMA, 2005
A 44-year-old woman reported several weeks of fatigue, somnolence, pain in the large joints, nausea, and decreased appetite. She had also noted an unintentional 11-kg weight loss over a period of 6 months. She had a remote history of amenorrhea, but she was presently menstruating regularly.
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A 44-year-old woman reported several weeks of fatigue, somnolence, pain in the large joints, nausea, and decreased appetite. She had also noted an unintentional 11-kg weight loss over a period of 6 months. She had a remote history of amenorrhea, but she was presently menstruating regularly.
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Pediatrics in Review, 2015
Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis.
Moises, Auron, Nouhad, Raissouni
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Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis.
Moises, Auron, Nouhad, Raissouni
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Therapies for adrenal insufficiency
Expert Opinion on Therapeutic Patents, 2007Adrenal insufficiency is a rare disorder in which the adrenal cortex fails to secrete sufficient amounts of steroid hormones. All adrenal hormones are affected in primary adrenal insufficiency, whereas only glucocorticoid secretion is deficient in secondary adrenal insufficiency.
M. Andrioli +3 more
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2010
The contribution of adrenal insufficiency (AI) to the morbidity of critically ill patients is currently under renewed scrutiny. Activation of the hypothalamic-pituitary-adrenal (HPA) axis is an integral part of the organism's response to stress and so a thorough understanding of the normal functioning of the HPA axis and potential pathophysiological ...
Venkatesh, Bala, Cohen, Jeremy
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The contribution of adrenal insufficiency (AI) to the morbidity of critically ill patients is currently under renewed scrutiny. Activation of the hypothalamic-pituitary-adrenal (HPA) axis is an integral part of the organism's response to stress and so a thorough understanding of the normal functioning of the HPA axis and potential pathophysiological ...
Venkatesh, Bala, Cohen, Jeremy
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Archives of Internal Medicine, 1954
CLINICALLY, it has been established that the prolonged use of cortisone results in a temporary depression of the adrenal secretions. It is this depressive effect on adrenal function that makes it possible to control carcinoma of the prostate gland after orchectomy and the estrogens have lost their therapeutic effect.
W A, KEITZER, P E, CHEER
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CLINICALLY, it has been established that the prolonged use of cortisone results in a temporary depression of the adrenal secretions. It is this depressive effect on adrenal function that makes it possible to control carcinoma of the prostate gland after orchectomy and the estrogens have lost their therapeutic effect.
W A, KEITZER, P E, CHEER
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Endocrinology and Metabolism Clinics of North America, 1993
Acute adrenal insufficiency is a rare disorder associated with high morbidity and mortality if allowed to progress unrecognized. A constellation of nonspecific symptoms including weakness, easy fatigue, nausea, anorexia, and weight loss are typical features of adrenal insufficiency.
S S, Werbel, K P, Ober
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Acute adrenal insufficiency is a rare disorder associated with high morbidity and mortality if allowed to progress unrecognized. A constellation of nonspecific symptoms including weakness, easy fatigue, nausea, anorexia, and weight loss are typical features of adrenal insufficiency.
S S, Werbel, K P, Ober
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Adrenal insufficiency in infancy
The Journal of Pediatrics, 1954Summary 1. An additional case of adrenogenital syndrome with adrenal insufficiency of a female pseudohermaphrodite at the age of 5 weeks is reported. 2. Early diagnosis and prompt therapyprobably averted the death of the infant. 3. Adrenal insufficiency was confirmed by the laboratory findings as well as by the subsequent improvement on a ...
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