Results 261 to 270 of about 52,427 (298)
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Journal of Surgical Oncology, 2012
AbstractAdrenocortical insufficiency may arise through primary failure of the adrenal glands or due to lack of ACTH stimulation as a result of pituitary or hypothalamic dysfunction. Prolonged administration of exogenous steroids will suppress the hypothalamic–pituitary‐adrenal axis, and hence cortisol secretion.
Melissa, Li-Ng, Laurence, Kennedy
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AbstractAdrenocortical insufficiency may arise through primary failure of the adrenal glands or due to lack of ACTH stimulation as a result of pituitary or hypothalamic dysfunction. Prolonged administration of exogenous steroids will suppress the hypothalamic–pituitary‐adrenal axis, and hence cortisol secretion.
Melissa, Li-Ng, Laurence, Kennedy
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Sepsis and Adrenal Insufficiency
Journal of Intensive Care Medicine, 2023In sepsis, dysregulation of the hypothalamic–pituitary–adrenal axis, alterations in cortisol metabolism, and tissue resistance to glucocorticoids can all result in relative adrenal insufficiency or critical illness-related corticosteroid insufficiency (CIRCI).
Cosmo Fowler +2 more
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JAMA, 2005
A 44-year-old woman reported several weeks of fatigue, somnolence, pain in the large joints, nausea, and decreased appetite. She had also noted an unintentional 11-kg weight loss over a period of 6 months. She had a remote history of amenorrhea, but she was presently menstruating regularly.
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A 44-year-old woman reported several weeks of fatigue, somnolence, pain in the large joints, nausea, and decreased appetite. She had also noted an unintentional 11-kg weight loss over a period of 6 months. She had a remote history of amenorrhea, but she was presently menstruating regularly.
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Pediatrics in Review, 2015
Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis.
Moises, Auron, Nouhad, Raissouni
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Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis.
Moises, Auron, Nouhad, Raissouni
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Archives of Internal Medicine, 1954
CLINICALLY, it has been established that the prolonged use of cortisone results in a temporary depression of the adrenal secretions. It is this depressive effect on adrenal function that makes it possible to control carcinoma of the prostate gland after orchectomy and the estrogens have lost their therapeutic effect.
W A, KEITZER, P E, CHEER
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CLINICALLY, it has been established that the prolonged use of cortisone results in a temporary depression of the adrenal secretions. It is this depressive effect on adrenal function that makes it possible to control carcinoma of the prostate gland after orchectomy and the estrogens have lost their therapeutic effect.
W A, KEITZER, P E, CHEER
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Endocrinology and Metabolism Clinics of North America, 1993
Acute adrenal insufficiency is a rare disorder associated with high morbidity and mortality if allowed to progress unrecognized. A constellation of nonspecific symptoms including weakness, easy fatigue, nausea, anorexia, and weight loss are typical features of adrenal insufficiency.
S S, Werbel, K P, Ober
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Acute adrenal insufficiency is a rare disorder associated with high morbidity and mortality if allowed to progress unrecognized. A constellation of nonspecific symptoms including weakness, easy fatigue, nausea, anorexia, and weight loss are typical features of adrenal insufficiency.
S S, Werbel, K P, Ober
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Therapies for adrenal insufficiency
Expert Opinion on Pharmacotherapy, 2007Adrenal insufficiency is a life-threatening disorder. In the treatment of adrenal insufficiency, it is essential to administer the optimal medication at the optimal dose. Glucocorticoids are the main therapeutic approach in all forms of adrenal insufficiency.
Kenji, Oki, Kiminori, Yamane
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Adrenal insufficiency in infancy
The Journal of Pediatrics, 1954Summary 1. An additional case of adrenogenital syndrome with adrenal insufficiency of a female pseudohermaphrodite at the age of 5 weeks is reported. 2. Early diagnosis and prompt therapyprobably averted the death of the infant. 3. Adrenal insufficiency was confirmed by the laboratory findings as well as by the subsequent improvement on a ...
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Relative adrenal insufficiency
Current Opinion in Endocrinology, Diabetes & Obesity, 2009This article will review the clinical presentation, diagnosis, and treatment of acute adrenal insufficiency and explore the concept of 'relative adrenal insufficiency' in the critically ill.Current dogma suggests that as many as 70% of patients in intensive care units with the clinical syndromes of sepsis or cardiogenic shock have 'relative adrenal ...
Donald L, Loriaux, Maria, Fleseriu
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IRREVERSIBILITY IN ADRENAL INSUFFICIENCY
The Journal of Nervous and Mental Disease, 1933In our earlier work (Hartman, Griffith and Hartman) with cortin, we observed that “If the animal reached the stage of prostration, the injection of cortical extracts was useless in most instances.” Whether this was due to inadequate dosage or to some irreversible change in the organism was not determined.
FRANK A. HARTMAN, CHARLES A. WINTER
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