Results 61 to 70 of about 82,412 (330)

Pre-hospital management of acute Addison’s Disease – Audit of patients attending a referral hospital in a regional area [PDF]

, 2019
Context: Adrenal crises (AC) cause morbidity and mortality in patients with Addison’s disease [primary adrenal insufficiency (PAI)]. Patient-initiated oral stress dosing, with parenteral hydrocortisone, is recommended to avert ACs. While these should be
Goubar, Thomas, McGrath, Shaun, Rushworth, R Louise, Torpy, David J   +3 more
core   +1 more source

Safer care for patients with adrenal insufficiency: weighing the evidence, balancing risks and acknowledging uncertainties [PDF]

, 2021
Michael Stacey, Robert M. Gifford, David R. Woods   +2 more
openalex   +1 more source

Adrenal insufficiency with enlarged adrenals

Abdominal Imaging, 1996
Five patients with adrenal insufficiency and large adrenal glands at presentation are reported. Addison's disease was due to adrenal tuberculosis in three patients, with important changes in adrenal configuration on CT reflecting the natural history of the disease.
Efremidis, S. C., Harsoulis, F., Douma, S., Zafiriadou, E., Zamboulis, C., Kouri, A.   +5 more
openaire   +3 more sources

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Introduction: Patients with primary adrenal insufficiency receive long - term glucocorticoid replacement therapy, which may cause osteoporosis [PDF]

, 2021
Peter Vaňuga, Ivana Ságová
openalex   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Current Approach for Diagnosis and Treatment of Adrenal Tuberculosis—Our Experience and Review of Literature

The Surgery Journal, 2022
Addison's disease was first described by Thomas Addison in 1855. He demonstrated the destruction of bilateral adrenal gland by tuberculosis (TB) in six patients.
Stuti Gupta, Md Abu Masud Ansari, Arun Kumar Gupta, Poras Chaudhary, Lalit Kumar Bansal   +4 more
doaj   +1 more source

Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia [PDF]

, 2012
Background Glucocorticoids play a major role in the treatment of acute lymphoblastic leukaemia (ALL). However, supraphysiological doses may cause suppression of the hypothalamic-pituitary-adrenal (HPA) axis.
Abdu, Agwu, Albert, Bessho, Birkebaek, Böttner, Christensen, Cunha, Dickstein, Einaudi, Felder-Puig, Felner, Grimes, Henzen, Hettmannsperger, Hurwitz, Igarashi, Krasner, Kuperman, Laupacis, Lightner, Maghnie, Mahachoklertwattana, Nyhlén, Pawlaczyk, Petersen, Planey, Poele, Pruckner, Rao, Rix, Rubnitz, Schlaghecke, Shah, Shibata, Shulman, Silva, Tijn, Tordjman, Vanderschueren-Lodeweyckx, Waage, Wheeler   +41 more
core   +2 more sources

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Pediatric Adrenal Insufficiency: Challenges and Solutions

Therapeutics and Clinical Risk Management, 2022
Daniela Nisticò,1 Benedetta Bossini,1 Simone Benvenuto,1 Maria Chiara Pellegrin,1 Gianluca Tornese2 1University of Trieste, Trieste, Italy; 2Department of Pediatrics, Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste ...
Nisticò D, Bossini B, Benvenuto S, Pellegrin MC, Tornese G   +4 more
doaj