Results 71 to 80 of about 114,029 (285)

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Clinical, Biochemical, and Radiological Characteristics of a Single-Center Retrospective Cohort of 705 Large Adrenal Tumors

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2018
Objective: To characterize large adrenal tumors (≥4 cm in diameter) and to identify features associated with malignancy. Patients and Methods: We investigated the clinical, biochemical, and imaging characteristics in a large retrospective single-center ...
Nicole M. Iñiguez-Ariza, MD, Jacob D. Kohlenberg, MD, Danae A. Delivanis, MD, Robert P. Hartman, MD, Diana S. Dean, MD, Melinda A. Thomas, BS, Muhammad Z. Shah, MD, Justine Herndon, PA-C, Travis J. McKenzie, MD, Wiebke Arlt, MD, DSc, William F. Young, Jr., MD, Irina Bancos, MD   +11 more
doaj   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

Laparoscopic and Endoscopic Cooperative Surgery for Gastric Cancer as an Alternative Treatment in Elderly Patients: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
In a prospective study of 20 elderly gastric cancer patients who declined gastrectomy, laparoscopic and endoscopic cooperative surgery (LECS) was technically safe and preserved postoperative function. However, as oncological curability cannot be assured in advanced cases, careful selection and informed consent are essential.
Marie Washio, Keishi Yamashita, Takuya Wada, Mikiko Sakuraya, Hiroki Harada, Tadashi Higuchi, Koshi Kumagai, Yasushi Orihashi, Chika Kusano, Naoki Hiki   +9 more
wiley   +1 more source

Pathohistological Diagnosis of Adrenal Tumors: Experience of a Single Center

Southeastern European Medical Journal, 2020
Introduction: To investigate adrenal tumors of patients operated on at the University Hospital Center Osijek from 2016 to 2019 for the purpose of examining the location and histopathological findings of the tumors and determining whether there is a ...
Ivan Lekić, Veronika Banović, Ksenija Marjanović, Borna Kovačić, Ivan Feldi, Tatjana Bačun   +5 more
doaj   +1 more source

Focal Spot, Spring 1994 [PDF]

, 1994
https://digitalcommons.wustl.edu/focal_spot_archives/1066/thumbnail ...

core   +1 more source

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara, Yasunori Kurahashi, Jun Watanabe, Yuichi Nagakawa, Tatsuro Nakamura, Eiichiro Nakao, Yudai Hojo, Shugo Kohno, Motoki Murakami, Yoshinori Ishida   +9 more
wiley   +1 more source

A case of adrenal cavernous hemangioma resected due to tumor growth accompanied by intratumoral hemorrhage

IJU Case Reports
Introduction We describe a case of an adrenal cavernous hemangioma that was surgically resected because of tumor growth and intratumoral hemorrhage.
Takayuki Ueda, Masato Yanagi, Takashi Kusakabe, Takeshi Shigihara, Mikio Shibasaki, Masato Nagasawa, Tsutomu Hamasaki, Yukihiro Kondo   +7 more
doaj   +1 more source