Results 101 to 110 of about 19,181 (247)

Delivery of nano‐formulated drugs to solid tumours is selectively increased by co‐application of the vascular disrupting agent CA4P

British Journal of Pharmacology, EarlyView.
Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski, Constanze Heise, Stefanie Sperling, Jasmin Hotz, Danica Bajic, Marina Rubey, Kathrin Klar, Georg Höfner, Julien Vollaire, Veronique Josserand, Jean‐Luc Coll, Oliver Thorn‐Seshold, Petar Marinković, Julia Thorn‐Seshold   +13 more
wiley   +1 more source

A case of Adrenocoricotrophic hormone -independent bilateral adrenocortical macronodular hyperplasia concomitant with primary aldosteronism

BMC Surgery, 2017
Background Adrenocoricotrophic hormone (ACTH) – independent bilateral adrenocortical macronodular hyperplasia (AIMAH) is a rare cause of Cushing’s syndrome, and is characterized by bilateral adrenal hyperplasia.
Mao Tokumoto, Naoyoshi Onoda, Yukie Tauchi, Shinichiro Kashiwagi, Satoru Noda, Norikazu Toi, Masahumi Kurajoh, Masahiko Ohsawa, Yuto Yamazaki, Hironobu Sasano, Kosei Hirakawa, Masaichi Ohira   +11 more
doaj   +1 more source

Improvement of Health‐Related Quality of Life and Mental Health After Unilateral Adrenalectomy for Primary Aldosteronism

Clinical Endocrinology, EarlyView.
ABSTRACT Background Primary aldosteronism (PA) has been linked with reduced health‐related quality of life (QoL) and increased prevalence of anxiety and depression. While most studies compared patients with PA to healthy subjects, this study focused on comparison with hypertensive patients without PA to identify PA‐specific effects.
Sybille Fuld, Christian Adolf, Georgiana Constantinescu, Manuel Schulze, Denise Brüdgam, Carmina T. Fuss, Hanna Remde, Lydia Kürzinger, Sven Gruber, Jun Yang, Amy Kang, Martin Reincke, Felix Beuschlein, Graeme Eisenhofer, Jacques W. M. Lenders, Christina Pamporaki   +15 more
wiley   +1 more source

Successful lateralization by adrenal vein sampling in a patient of primary aldosteronism on concurrent mineralocorticoid receptor antagonist: Time to change the narrative

Endocrine and Metabolic Science
Introduction: Primary aldosteronism (PA) is the most common endocrine cause of hypertension. Untreated PA carries a high cardiovascular morbidity and mortality.
Rujul Jain, Navein Thomas John, Pushpender Khatana   +2 more
doaj   +1 more source

Adrenal venous sampling in a patient with adrenal Cushing syndrome.

Colombia medica (Cali, Colombia), 2016
RESUMEN: La hiperplasia macro nodular bilateral o hiperplasia adrenal nodular bilateral independiente de la hormona adrenocorticotrópica es una de las causas menos frecuentes de hipercortisolismo, su diagnóstico supone un reto y no se tiene claridad de cuál es la mejor aproximación terapéutica.
Builes Montaño, Carlos Esteban, Villa Franco, Carlos Andrés, Román González, Alejandro, Vélez Hoyos, Alejandro, Echeverri Isaza, Santiago   +4 more
openaire   +3 more sources

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

Somatostatin receptor scintigraphy: Its value in tumor localization in patients with Cushing's syndrome caused by ectopic corticotropin or corticotropin-releasing hormone secretion [PDF]

, 1994
purpose: To assess the feasibility of somatostatin receptor scintigraphy for patients with Cushing's syndrome caused by tumors secreting ectopic corticotropin or corticotropin-releasing hormone (CRH).
Bruining, H.A. (Hajo), Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Kreniming, E.P. (Eric), Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Malchoff, C.D. (Carl), Nobels, F.R.E. (Frank), Oei, H.Y. (H.), Pols, H.A.P. (Huib), Reubi, J.-C. (Jean-Claude)   +10 more
core   +1 more source

Diagnosis of Growth Hormone Deficiency in Children: Comparative Performance of Arginine Versus Glucagon as the First Stimulation Test

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Growth hormone deficiency (GHD) diagnosis typically requires the performance of two sequential stimulation tests. Glucagon stimulation test (GST) and arginine stimulation test (AST) are widely used. This study aimed to determine the most suitable order of tests.
David Shaki, Daria Shvarts, Eli Hershkovitz, Lior Carmon, Hazan Guy, Bachar Yoav, Alon Haim   +6 more
wiley   +1 more source

Adrenaline Bi-Enzyme Sensor Using Signal Amplification Principle to Support Adrenal Venous Sampling

Proceedings, 2017
Primary aldosteronsim (PA) is the most frequent cause of secondary hypertension. [...]
Denise Molinnus, Gabriel Hardt, Petra Siegert, Holger S. Willenberg, Fred Lisdat, Arshak Poghossian, Michael Keusgen, Michael J. Schöning   +7 more
doaj   +1 more source

Salivary cortisol to assess the hypothalamic-pituitary-adrenal axisin healthy children under 3 years old [PDF]

, 2007
OBJECTIVE: To establish reference concentration intervals for salivary cortisol in healthy children, in the morning and in the afternoon, investigating factors that interfere with the concentration measured and the possibility that circadian rhythms are ...
Ferrari, Giesela F., Mallozi, Marcia Carvalho, Silva, Margarete L.   +2 more
core   +2 more sources