Results 81 to 90 of about 2,656,127 (223)

Does concomitant autonomous adrenal cortisol overproduction have the potential to confound the interpretation of adrenal venous sampling in primary aldosteronism?

open access: yes, 2015
Objective Demonstration of unilateral aldosterone production by adrenal venous sampling (AVS) is required to select appropriate candidates for adrenalectomy in patients with primary aldosteronism (PA).
Wolley, Martin   +14 more
core   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang   +7 more
wiley   +1 more source

Effect of Cyclic Heat Exposure on the Growth Performance and Metabolism of Broilers Fed Palm Kernel Meal

open access: yesAnimal Research and One Health, EarlyView.
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa   +13 more
wiley   +1 more source

Selective Use of Adrenal Venous Sampling in the Lateralization of Aldosterone-producing Adenomas

open access: yes, 2006
It has been suggested that routine adrenal venous sampling (AVS) is necessary to lateralize an aldosterone-producing adenoma in patients with primary hyperaldosteronism. However, the success rate of AVS is variable, with potential risks.
Yah Yuen Tan   +13 more
core   +1 more source

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

open access: yesAnimal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren   +6 more
wiley   +1 more source

Maternal overweight and obesity during pregnancy and sex‐dependent dysregulation of the materno‐fetal stress axis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Maternal obesity and excess gestational weight gain (GWG) are linked to adverse perinatal outcomes, potentially via disruption of the maternal–fetal stress axis. Placental HSD11B2 protects the fetus from excess glucocorticoids and may influence fetal programming during maternal metabolic stress.
Thorsten Braun   +13 more
wiley   +1 more source

Utility of microcatheter in adrenal venous sampling for primary aldosteronism

open access: yesThe British Journal of Radiology, 2020
Objective: To evaluate the utility of microcatheter in adrenal venous sampling (AVS) for assessing aldosterone hypersecretion and the laterality in patients with primary aldosteronism. Methods: This retrospective study was approved by the ...
Yoshifumi, Noda   +9 more
openaire   +3 more sources

System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis

open access: yesiMetaMed, EarlyView.
This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...
Bixing Fang   +13 more
wiley   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

open access: yesiMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang   +10 more
wiley   +1 more source

Sex‐Specific Early Life Corticosterone Stress‐Coping Capacity Is Linked to Mitochondrial Content and Telomere Maintenance

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Glucocorticoids are upregulated during acute challenges, contributing to maintenance of energy balance. However, if this upregulation exceeds a threshold or becomes chronic, it can lead to harmful effects. Investigating the factors behind between‐individual variation in the magnitude of the response to acute stress and how effectively ...
Mauricio Guillen‐Parra   +3 more
wiley   +1 more source

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