Results 61 to 70 of about 2,511,193 (234)

Diagnostic utility of data from adrenal venous sampling for primary aldosteronism despite failed cannulation of the right adrenal vein.

, 2016
BackgroundAdrenal venous sampling is an important lateralization study for primary aldosteronism, but inability to cannulate the right adrenal vein is not uncommon and interpreted as a failed study.
Shen, Wen T, Suh, Insoo, Wingo, Matt, Seiser, Natalie, Pasternak, Jesse D, Herman, Max, Cowan, Vanessa, Lee, James A, Gosnell, Jessica E, Duh, Quan-Yang, Epelboym, Irene, Kerlan, Robert K   +11 more
core   +1 more source

The role of adrenal venous sampling in the surgical management of primary aldosteronism

, 2006
Objective: Primary aldosteronism is the most common endocrine form of secondary hypertension, but no single test or imaging method always identifies it.
PELIZZO, MARIA ROSA, BERNANTE, PAOLO, TONIATO, ANTONIO, ROSSI, GIANPAOLO   +3 more
core   +2 more sources

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Role of radiologists in the diagnosis and management of adrenal disorders

Endocrine Journal
This study aimed to focus on the role of radiologists in the diagnosis and management of adrenal lesions, particularly primary aldosteronism (PA) and secondary hypertension.
Sota Oguro, Hiromitsu Tannai, Hideki Ota, Kazumasa Seiji, Hiroki Kamada, Yoshitaka Toyama, Kei Omata, Yuta Tezuka, Yoshikiyo Ono, Fumitoshi Satoh, Sadayoshi Ito, Tetsuhiro Tanaka, Hideki Katagiri, Kei Takase   +13 more
doaj   +1 more source

Adrenal venous sampling in the diagnostic workup of primary aldosteronism

The British Journal of Radiology, 2021
Primary aldosteronism (PA) is the primary cause of secondary hypertension. The prevalence of PA has probably been underestimated in the past and recent studies suggest that PA could be present in up to 10% of patients suffering from hypertension. Aldosterone excess in PA can be caused by unilateral adrenal disease, usually adrenal adenoma, or bilateral
Matthias Johannes Betz, Christoph Johannes Zech   +1 more
openaire   +2 more sources

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Case Report: A hybrid approach of selective adrenal artery and venous embolization for the treatment of unilateral aldosterone-producing adenoma

Frontiers in Cardiovascular Medicine
Selective adrenal artery embolization (SAAE) has emerged as a promising minimally invasive alternative to traditional therapies for primary aldosteronism (PA).
Changqiang Yang, Changqiang Yang, Changqiang Yang, Sen Liu, Sen Liu, Sen Liu, Peijian Wang, Peijian Wang, Peijian Wang   +8 more
doaj   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Integration of clinical parameters and CT-based radiomics improves machine learning assisted subtyping of primary hyperaldosteronism

Frontiers in Endocrinology, 2023
ObjectivesThe aim of this study was to investigate an integrated diagnostics approach for prediction of the source of aldosterone overproduction in primary hyperaldosteronism (PA).Methods269 patients from the prospective German Conn Registry with PA were
Nabeel Mansour, Andreas Mittermeier, Roman Walter, Balthasar Schachtner, Jan Rudolph, Bernd Erber, Vanessa F. Schmidt, Daniel Heinrich, Denise Bruedgam, Lea Tschaidse, Hanna Nowotny, Martin Bidlingmaier, Sonja L. Kunz, Christian Adolf, Jens Ricke, Martin Reincke, Nicole Reisch, Moritz Wildgruber, Michael Ingrisch   +18 more
doaj   +1 more source