Results 121 to 130 of about 468,250 (391)

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

Molecular Profiling of Genes Associated With Methylphenidate Pathway Therapy and Discovery of New Variants in Amazonian Amerindian Populations

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos, Tatiane Carinta de Souza, Kaio Evandro Cardoso Aguiar, Ana Caroline Alves da Costa, Natasha Monte, Juliana Carla Gomes Rodrigues, Giovanna Gilioli da Costa Nunes, Rita de Cássia Calderaro Coelho, Ândrea Ribeiro‐dos‐Santos, André Maurício Ribeiro dos Santos, Sandro José de Souza, Sidney Emanuel Batista dos Santos, Rommel Mario Rodriguez Burbano, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +14 more
wiley   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Adrenergic α_2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice [PDF]

, 1998
Jukka Sallinen, Antti Haapalinna, Timo Viitamaa, Brian K. Kobilka, Mika Scheinin   +4 more
openalex   +1 more source

The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

Nature, 2010
β-adrenergic receptors (βARs) are G-protein-coupled receptors (GPCRs) that activate intracellular G proteins upon binding catecholamine agonist ligands such as adrenaline and noradrenaline.
Tony Warne, R. Moukhametzianov, J. Baker, Rony Nehmé, P. Edwards, A. Leslie, G. Schertler, C. Tate   +7 more
semanticscholar   +1 more source

The tiger salamander as a promising alternative model organism to the axolotl for fracture healing and regenerative biology research

The Anatomical Record, EarlyView.
Abstract Scientists have been captivated by the ability to regenerate, focusing on uncovering the mechanisms of epimorphic regeneration and applying them to human medicine. The axolotl (Ambystoma mexicanum) has become the most intensively studied model in tetrapod regeneration research, particularly concerning limb regeneration.
Vivien Bothe, Nadia Fröbisch
wiley   +1 more source

Sex-Related Effects of Prenatal Stress on Region-Specific Expression of Monoamine Oxidase A and β Adrenergic Receptors in Rat Hearts

Arquivos Brasileiros de Cardiologia, 2018
Background: Prenatal stress may increase risk of developing cardiovascular disorders in adulthood. The cardiotoxic effects of catecholamines are mediated via prolonged adrenergic receptor stimulation and increased oxidative stress upon their degradation ...
Tanja Jevjdovic, Tamara Dakic, Sonja Kopanja, Iva Lakic, Predrag Vujovic, Nebojsa Jasnic, Jelena Djordjevic   +6 more
doaj   +1 more source

In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft. [PDF]

, 1998
PurposeTo assess the response of rat urinary bladder regenerated by the homologous bladder acellular matrix graft (BAMG) to in vitro electrical and pharmacologic stimuli.Materials and methodsIn Sprague-Dawley rats, partial cystectomy (>50%) was ...
Dahiya, R, Dahms, SE, Lue, TF, Nunes, LS, Piechota, HJ, Tanagho, EA   +5 more
core   +1 more source

Molecular biology of amitraz resistance in cattle ticks of the genus Rhipicephalus [PDF]

, 2018
Amitraz is an important product for the control of cattle ticks around the world. In comparison with other products for the control of ticks, it is quite affordable and it has a rapid knock-down effect.
Berry, Christina M., Corley, Sean W., Jonsson, Nicholas N., Klafke, Guilherme, Koh-Tan, H.H. Caline, Tidwell, Jason   +5 more
core   +1 more source

Possible association of β2- and β3-adrenergic receptor gene polymorphisms with susceptibility to breast cancer [PDF]

, 2001
Xin‐En Huang, Nobuyuki Hamajima, Toshiko Saito, Keitaro Matsuo, Mitsuhiro Mizutani, Hiroji Iwata, Takuji Iwase, Shigeto Miura, Tsutomu Mizuno, Shinkan Tokudome, Kazuo Tajima   +10 more
openalex   +1 more source