Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang +5 more
wiley +1 more source
Synephrine potentiates lidocaine-induced cutaneous analgesia via α-adrenergic receptors in male rats. [PDF]
Chou AK +5 more
europepmc +1 more source
β3-Adrenergic agonist induces a functionally active uncoupling protein in fat and slow-twitch muscle fibers [PDF]
Toshihide Yoshida +9 more
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Histamine infusions induce reproducible severe hypotension. Intramuscular adrenaline showed ‘supposedly therapeutic’ plasma concentrations but did not produce a sustained clinically relevant improvement in shock in the majority of recipients. These findings question adrenaline pharmacokinetic surrogate thresholds and support the need for faster and ...
Matthias Weiss‐Tessbach +12 more
wiley +1 more source
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)
Rajika Roy, PhD, Walter J. Koch, PhD
doaj +1 more source
Neural Innervation of Tumors: Mechanisms, Hallmarks, and Therapeutic Opportunities. [PDF]
Cassim S, Montemagno C.
europepmc +1 more source
Does caffeine confound relationships among adrenergic tone, blood pressure and sleep apnoea? [PDF]
Bardwell +6 more
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Summary Introduction Phenylephrine infusion is widely endorsed by guidelines as the preferred prophylactic drug for spinal hypotension in patients undergoing caesarean delivery; however, clinical practice continues to show marked variability in the selection of vasopressor drugs.
Narinder Pal Singh +4 more
wiley +1 more source
Fibre Type-Specific Proteomics Reveals Shared and Distinct Skeletal Muscle Adaptations to Resistance Training and Beta<sub>2</sub>-Adrenergic Agonist. [PDF]
Jessen S +9 more
europepmc +1 more source
Beta-adrenergic regulation of pancreatic cancer progression
Corina Kim-Fuchs
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