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International Journal of Biochemistry and Cell Biology, 2010 Lipolysis in adipocytes, the hydrolysis of triacylglycerol (TAG) to release fatty acids (FAs) and glycerol for use by other organs, is a unique function of white adipose tissue. Lipolysis in adipocytes occurs at the surface of cytosolic lipid droplets, which have recently gained much attention as dynamic organelles integral to lipid metabolism ...
Maryam Ahmadian, Hei Sook Sul
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Molecular Metabolism, 2020 Objectives: Lipolysis, hydrolysis of triglycerides to fatty acids in adipocytes, is tightly regulated, poorly understood, and, if perturbed, can lead to metabolic diseases including obesity and type 2 diabetes.
Agné Kulyte +2 more
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Regulation of Lipolysis in Adipocytes [PDF]
Annual Review of Nutrition, 2007 Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and nonesterified fatty acids that are released into the vasculature for use by other organs as energy substrates. In response to changes in nutritional state, lipolysis rates are precisely regulated through hormonal and biochemical signals.
Maryam Ahmadian +2 more
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Antilipolytic actions of insulin on basal and hormone-induced lipolysis in rat adipocytes
Journal of Lipid Research, 1998 The levels of insulin, free fatty acids (FFA), and triglycerides in rat sera increase with age. The increase in serum FFA levels accompanied the stimulation of basal lipolysis (i.e., lipolysis in the absence of lipolytic agents) in fat cells and ...
Chie Morimoto +2 more
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Molecular Metabolism, 2023 Objectives: Insulin's ability to counterbalance catecholamine-induced lipolysis defines insulin action in adipose tissue. Insulin suppresses lipolysis directly at the level of the adipocyte and indirectly through signaling in the brain.
Matthäus Metz +5 more
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Phospholipid Degradation Kinetics of Pork during Combined High-Pressure and Thermal Treatments [PDF]
Shipin Kexue, 2023 In order to explore the effect of combined high-pressure and thermal treatment on the lipolysis of phospholipids in pork, the phospholipid degradation kinetics of pork was studied in the 300 to 700 MPa pressure range and in the 20 to 60 ℃ temperature ...
YUN Zhoumiao, HUANG Yechuan, PENG Chunlei, ZHAO Jing, ZHANG Keyuan
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Butyrate and other short-chain fatty acids increase the rate of lipolysis in 3T3-L1 adipocytes [PDF]
PeerJ, 2014 We determined the effect of butyrate and other short-chain fatty acids (SCFA) on rates of lipolysis in 3T3-L1 adipocytes. Prolonged treatment with butyrate (5 mM) increased the rate of lipolysis approximately 2–3-fold.
John M. Rumberger +2 more
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Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture
Frontiers in Endocrinology, 2023 The inhibitory effect of growth hormone (GH) on adipose tissue growth and the stimulatory effect of GH on lipolysis are well known, but the mechanisms underlying these effects are not completely understood.
Lidan Zhao, Honglin Jiang
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Measurement of Lipolysis [PDF]
, 2014 Lipolysis is defined as the hydrolytic cleavage of ester bonds in triglycerides (TGs), resulting in the generation of fatty acids (FAs) and glycerol. The two major TG pools in the body of vertebrates comprise intracellular TGs and plasma/nutritional TGs.
Martina, Schweiger +5 more
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The Journal of Cell Biology, 2003 Successful adaptation to starvation in mammals depends heavily on the regulated mobilization of fatty acids from triacylglycerols stored in adipose tissue. Although it has long been recognized that cyclic AMP represents the critical second messenger and hormone-sensitive lipase (HSL)**Abbreviations used in this paper: ADRP, adipocyte differentiation ...
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