Results 21 to 30 of about 66,901 (164)

DHA induces adipocyte lipolysis through endoplasmic reticulum stress and the cAMP/PKA signaling pathway in grass carp (Ctenopharyngodon idella)

open access: yesAnimal Nutrition, 2023
Docosahexaenoic acid (DHA) is a biologically active fatty acid that reduces the accumulation of lipids. However, the molecular mechanism underlying this process, particularly in fish, is not well understood. Recent studies show that endoplasmic reticulum
Xiaocheng Huang   +4 more
doaj   +1 more source

A Future for Injection Lipolysis? [PDF]

open access: yesAesthetic Surgery Journal, 2013
Nearly a decade has passed since we first began our audit of clinical outcomes using multiple subcutaneous injections of the lipodissolve agent Lipostabil N (Sanofi-Aventis, Frankfurt, Germany) to reduce adipose deposits in the abdomen and other areas.1 That lipodissolve agent contained phosphatidylcholine (PC) and deoxycholate (DC) as active ...
Brent, Tanner   +3 more
openaire   +2 more sources

GPIHBP1 and lipolysis: an update [PDF]

open access: yesCurrent Opinion in Lipidology, 2009
This review will provide an update on the structure of GPIHBP1, a 28-kDa glycosylphosphatidylinositol-anchored glycoprotein, and its role in the lipolytic processing of triglyceride-rich lipoproteins.Gpihbp1 knockout mice on a chow diet have milky plasma and plasma triglyceride levels of more than 3000 mg/dl.
Anne P, Beigneux   +6 more
openaire   +2 more sources

Suppression of adipose lipolysis by long-chain fatty acid analogs

open access: yesJournal of Lipid Research, 2012
Agonist-induced lipolysis of adipose fat is robustly inhibited by insulin or by feedback inhibition by the long-chain fatty acids (LCFA) produced during lipolysis. However, the mode of action of LCFA in suppressing adipose lipolysis is not clear.
Bella Kalderon   +5 more
doaj   +1 more source

Systemic Nanoparticle‐Mediated Delivery of Pantetheinase Vanin‐1 Regulates Lipolysis and Adiposity in Abdominal White Adipose Tissue

open access: yesAdvanced Science, 2020
Lipolysis in white adipose tissue (WAT) occurs in response to nutritional signals and helps to regulate lipid turnover/adiposity in animals. However, the causal relationships and the mechanisms controlling WAT morphology are not clear.
Siyu Chen   +8 more
doaj   +1 more source

Effect of epinephrine and other lipolytic agents on intracellular lipolysis and lipoprotein lipase activity in 3T3-L1 adipocytes.

open access: yesJournal of Lipid Research, 1987
3T3-L1 adipocytes were used to test the hypothesis that hormone-sensitive lipolysis and lipoprotein lipase activity might be regulated in a reciprocal manner.
S S Chernick   +3 more
doaj   +1 more source

Relationship between cyclic AMP production and lipolysis induced by forskolin in rat fat cells.

open access: yesJournal of Lipid Research, 1992
Forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) induced both cyclic AMP production and lipolysis in intact fat cells, but stimulated lipolysis without increasing cyclic AMP at a concentration of 10(-5) M ...
H Okuda, C Morimoto, T Tsujita
doaj   +1 more source

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVES:Numerous genetic loci have been associated with measures of central fat accumulation, such as waist-to-hip ratio adjusted for body mass index (WHRadjBMI).
Rona J Strawbridge   +7 more
doaj   +1 more source

Pharmacological inhibition of lipolysis prevents adverse metabolic outcomes during glucocorticoid administration

open access: yesMolecular Metabolism, 2023
Objective: Glucocorticoids are one of the most commonly prescribed classes of anti-inflammatory drugs; however, chronic treatment promotes iatrogenic (drug-induced) diabetes.
Melissa A. Linden   +10 more
doaj   +1 more source

Trichostatin A modulates thiazolidinedione-mediated suppression of tumor necrosis factor α-induced lipolysis in 3T3-L1 adipocytes. [PDF]

open access: yesPLoS ONE, 2013
In obesity, high levels of tumor necrosis factor α (TNFα) stimulate lipolysis in adipocytes, leading to hyperlipidemia and insulin resistance. Thiazolidinediones (TZDs), the insulin-sensitizing drugs, antagonize TNFα-induced lipolysis in adipocytes ...
Juu-Chin Lu   +5 more
doaj   +1 more source

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