Results 11 to 20 of about 66,901 (164)

Regulation of adipocyte lipolysis [PDF]

Nutrition Research Reviews, 2014
In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting conditions or times of elevated energy demands is tightly regulated by neuroendocrine signals, resulting in the activation of lipolytic enzymes. Among the classic regulators of lipolysis, adrenergic stimulation and the insulin-mediated control of lipid mobilisation ...
Gema, Frühbeck, Leire, Méndez-Giménez, José-Antonio, Fernández-Formoso, Secundino, Fernández, Amaia, Rodríguez   +4 more
openaire   +2 more sources

Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases

Journal of Lipid Research, 2005
Hormone-sensitive lipase (HSL) contributes importantly to the hydrolysis of cholesteryl ester in steroidogenic tissues, releasing the cholesterol required for adrenal steroidogenesis.
Yassine Ben Ali, Frédéric Carrière, Robert Verger, Stefan Petry, Günter Muller, Abdelkarim Abousalham   +5 more
doaj   +1 more source

Sensitive assay for hormone-sensitive lipase using NBD-labeled monoacylglycerol to detect low activities in rat adipocytes

Journal of Lipid Research, 2005
The recent finding that p-nitrobenzofurazan (NBD)-FA is incorporated into and released from the acylglycerols of isolated rat adipocytes in an insulin-sensitive manner [G. Müller, H. Jordan, C. Jung, H. Kleine, and S. Petry. 2003. Biochimie.
Stefan Petry, Yassine Ben Ali, Henri Chahinian, Holger Jordan, Horst Kleine, Günter Müller, Frédéric Carrière, Abdelkarim Abousalham   +7 more
doaj   +1 more source

Obstructive sleep apnoea increases lipolysis and deteriorates glucose homeostasis in patients with type 2 diabetes mellitus

Scientific Reports, 2021
Obstructive sleep apnoea (OSA) is associated with type 2 diabetes mellitus (T2DM). However, mechanisms mediating association between these two conditions remain unclear.
Minh Duc Trinh, Andrea Plihalova, Jan Gojda, Katerina Westlake, Jan Spicka, Zuzana Lattova, Martin Pretl, Jan Polak   +7 more
doaj   +1 more source

The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis

Journal of Lipid Research, 2005
This study assessed the effects of selective inhibitors of 3′,5′-cyclic nucleotide phosphodiesterases (PDEs) on adipocyte lipolysis. IC224, a selective inhibitor of type 1 phosphodiesterase (PDE1), suppressed lipolysis in murine 3T3-L1 adipocytes (69.6 ±
Peter B. Snyder, James M. Esselstyn, Kate Loughney, Sharon L. Wolda, Vincent A. Florio   +4 more
doaj   +1 more source

The Molecular Brakes of Adipose Tissue Lipolysis

Frontiers in Physiology, 2022
Adaptation to changes in energy availability is pivotal for the survival of animals. Adipose tissue, the body’s largest reservoir of energy and a major source of metabolic fuel, exerts a buffering function for fluctuations in nutrient availability.
Yongguo Li, Zhen Li, Devi Anggraini Ngandiri, Mireia Llerins Perez, Alexander Wolf, Yuanyuan Wang   +5 more
doaj   +1 more source

Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia

Cell Death and Disease, 2021
Cancer cachexia is a metabolic disorder characterized by skeletal muscle wasting and white adipose tissue browning. Specific functions of several hormones, growth factors, and cytokines derived from tumors can trigger cachexia.
Wenjun Hu, Hairong Xiong, Zeyuan Ru, Yan Zhao, Yali Zhou, Kairu Xie, Wen Xiao, Zhiyong Xiong, Cheng Wang, Changfei Yuan, Jian Shi, Quansheng Du, Xiaoping Zhang, Hongmei Yang   +13 more
doaj   +1 more source

Rapid orbital lipolysis associated with critical illness and colectomy

Radiology Case Reports, 2021
Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described.
Joy Li, AB, Aikta Rajput, BS, David Kosoy, BS, Sari Umekawa, MD, Anuj Rajput, MD, Jessica Chang, MD, Vishal Patel, MD, PhD   +6 more
doaj   +1 more source

Gut microbiome is linked to functions of peripheral immune cells in transition cows during excessive lipolysis

Microbiome, 2023
Background Postpartum dairy cows experiencing excessive lipolysis are prone to severe immunosuppression. Despite the extensive understanding of the gut microbial regulation of host immunity and metabolism, its role during excessive lipolysis in cows is ...
Fengfei Gu, Senlin Zhu, Yifan Tang, Xiaohan Liu, Minghui Jia, Nilusha Malmuthuge, Teresa G. Valencak, Joseph W. McFadden, Jian-Xin Liu, Hui-Zeng Sun   +9 more
doaj   +1 more source

Dependence of rates of lipolysis, esterification, and free fatty acid release in isolated fat cells on age, cell size, and nutritional state

Journal of Lipid Research, 1973
Rates of lipolysis, esterification, and free fatty acid release were estimated in isolated epididymal fat cells prepared from rats fed either ad lib. or with a restricted caloric intake.
Michael F. Reardon, R. Brian Goldrick, Noel H. Fidge   +2 more
doaj   +1 more source