Results 251 to 260 of about 349,413 (344)

Nocturnal asthma [PDF]

open access: yes, 1991
Emslander, H.-P.   +7 more
core   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

open access: yesIntegrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang   +5 more
wiley   +1 more source

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

open access: yesAllergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco   +38 more
wiley   +1 more source

Modulation of inflammatory and adrenergic pathways in hypertension: effects of β-blockers on cytokine release in Jurkat T cells. [PDF]

open access: yesActa Biochim Pol
Kajaia N   +6 more
europepmc   +1 more source

Beta1-Adrenergic Agonist Is a Potent Stimulator of Alveolar Fluid Clearance in Hyperoxic Rat Lungs

open access: diamond, 2001
Tsutomu Sakuma   +8 more
openalex   +1 more source

Dorsal Genital Nerve Stimulation as an Adjunctive Therapy to Control Neurogenic Detrusor Overactivity After Spinal Cord Injury

open access: yesArtificial Organs, EarlyView.
People with spinal cord injury (SCI) experience bladder overactivity, which can cause incontinence. Dorsal genital nerve stimulation (DGNS) can suppress overactivity, providing a longer duration to reach a toilet. People with SCI trialed home‐based DGNS for 8 weeks. DGNS was effective in the laboratory, and participants found home‐based DGNS acceptable.
Sean Doherty   +4 more
wiley   +1 more source

Sepsis-induced hypocholesterolemia is linked to low cardiomyocyte membrane cholesterol and impaired catecholamine responsiveness. [PDF]

open access: yesCrit Care
Kleyman A   +14 more
europepmc   +1 more source

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht   +4 more
wiley   +1 more source

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