Results 251 to 260 of about 468,250 (391)

Across species: A comparative perspective on red cell homeostasis and its influence on our understanding of human physiology and disease

British Journal of Haematology, EarlyView.
This review highlights how studies on animal red cells have enriched our understanding of the behaviour of those from humans. A comparative perspective has enhanced our knowledge of human red cell pathophysiology Summary This review emphasises how studies on animal red cells have enriched our understanding of the behaviour of those from humans.
Kathleen M. Connolly, Pengyi Ding, Rasiqh Wadud, David C. Rees, John N. Brewin, John S. Gibson   +5 more
wiley   +1 more source

The Impact of Chronic Stress on Treatment Outcomes of Cancer Patients with Divergent Survival Rates: A Systematic Review. [PDF]

Int J Mol Sci
Herbetko K, Kaczor J, Sołtyk A, Kisielewska M, Opęchowski M, Sztuder A, Kulbacka J.   +6 more
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Chronic β-Blockade and Systemic Homeostasis: Molecular Integration of Cardiorenal and Immune Pathways, a Narrative Review. [PDF]

Biomolecules
Park J, Hamanaka A, Park I, Abdelhady HG.   +3 more
europepmc   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

In vivo and ex vivo cardiovascular haemodynamic responses of preterm growth-restricted lambs to perinatal asphyxia. [PDF]

Clin Sci (Lond)
Azman Z, Piscopo BR, Sutherland AE, Thiel A, Zahra VA, Pham Y, Nitsos I, Hossain MM, Malhotra A, Miller SL, Bubb KJ, Polglase GR, Allison BJ.   +12 more
europepmc   +1 more source

Effects of short-acting β-adrenergic blocker on B-type natriuretic peptide at early stage of postresuscitation in rabbits

, 2006
Xiang Li, Peijie Li, Yun-fen HE, Hong Zeng, Zili Li, Zhengyi Zhang, Wen Cao, Yang Lan   +7 more
openalex   +1 more source

Characterization of the Alpha-Kap FRET Biosensor to Determine Compartmentalized Beta-Adrenergic Receptor Camp Signaling in Distinct Intracellular Locations [PDF]

, 2019
Michael W. Rudokas, John P. Post, Alejandra Sataray‐Rodriguez, Chase M. Fiore, Shailesh R. Agarwal, Robert D. Harvey   +5 more
openalex   +1 more source

Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome.

New England Journal of Medicine, 1994
J. Shores, K. R. Berger, E. Murphy, R. Pyeritz   +3 more
semanticscholar   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source