Results 21 to 30 of about 16,552 (150)

The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality from COVID-19 [PDF]

, 2020
Abstract Effective therapies for coronavirus disease 2019 (COVID-19) are urgently needed, and preclinical data suggest alpha-1 adrenergic receptor antagonists (α 1 -AR antagonists) may be effective in reducing mortality related to hyperinflammation independent of etiology.
Liam Rose, Laura Graham, Allison Koenecke, Michael Powell, Ruoxuan Xiong, Zhu Shen, Kenneth W. Kinzler, Chetan Bettegowda, Bert Vogelstein, Susan Athey, Joshua T. Vogelstein, Maximilian F. Konig, Todd H. Wagner   +12 more
openaire   +2 more sources

Expression of bladder α1-adrenoceptor subtype after relief of partial bladder outlet obstruction in a rat model [PDF]

Investigative and Clinical Urology, 2020
Purpose: Many patients with benign prostatic hyperplasia require treatment for persistent storage symptoms, even when the obstruction is successfully relieved by surgery. Previous studies identified a characteristic increase in α1D-adrenoceptor levels in
Ji Yong Lee , Jong Mok Park , Yong Gil Na , Ki Hak Song , Jae Sung Lim , Seung Woo Yang , Gun Hwa Kim , Ju Hyun Shin   +7 more
doaj   +1 more source

Anti-inflammatory and antipyretic potential of Arbutus andrachne L. methanolic leaf extract in rats

Asian Pacific Journal of Tropical Biomedicine, 2021
Objective: To explore the anti-inflammatory and antipyretic effects of methanolic leaf extract from Arbutus andrachne and its mechanism of action. Methods: Paw edema was induced by intraplantar (i.pl.) injection of λ-carrageenan (1% w/v, 100 μL/paw ...
Sahar M Jaffal, Sawsan A Oran, Mohammad I Alsalem   +2 more
doaj   +1 more source

Benign prostatic hyperplasia: clinical treatment can complicate cataract surgery

International Brazilian Journal of Urology, 2010
PURPOSE: To investigate the effects of alpha-1 adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia (BPH) regarding potential risks of complications in the setting of cataract surgery. AIM: To address recommendations, optimal
Fernando Facio, Renata Kashiwabuschi, Yutaro Nishi, Ricardo Leao, Peter Mcdonnell, Arthur Burnett   +5 more
doaj   +1 more source

Impact of Intravesical Protrusion of the Prostate in the Treatment of Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia of Moderate Size by Alpha Receptor Antagonist [PDF]

International Neurourology Journal, 2012
Purpose To evaluate whether intravesical protrusion of the prostate (IPP) is related to the treatment effect of alpha-1 receptor antagonist in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) with a prostate size of ...
Yu Mi Seo, Hyung Jee Kim
doaj   +1 more source

Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. [PDF]

Proceedings of the National Academy of Sciences, 1985
Prazosin, an antagonist of alpha 1-adrenergic receptors, has been found to suppress the clinical and histological expression of experimental autoimmune encephalomyelitis (EAE) in the Lewis rat. Suppression was more significant in females than in males and was a dose-dependent phenomenon.
C F, Brosnan, E A, Goldmuntz, W, Cammer, S M, Factor, B R, Bloom, W T, Norton   +5 more
openaire   +2 more sources

The Impact of 5-Alpha Reductase Inhibitor vs. Alpha-1 Adrenergic Receptor Antagonists on Course of Prostate Premalignant Conditions [PDF]

Advances in Clinical and Experimental Medicine, 2014
Prostate intraepithelial neoplasm and atypical small acinar proliferation are considered prostate premalignant conditions. Such a diagnosis impacts further follow-up significantly as early detection of prostate cancer is of utmost importance. alpha-1 adrenergic receptor antagonists (i.e.
Mieczysław, Fryczkowski, Piotr, Bryniarski, Maciej, Szczębara, Andrzej, Paradysz   +3 more
openaire   +4 more sources

The use of alpha-1 adrenergic blockers in children with distal ureterolithiasis: a systematic review and meta-analysis

International Brazilian Journal of Urology, 2015
Introduction: Urinary lithiasis is the main urologic cause of emergency treatment in adult patient. In the past years, the incidence in children population has increased.
F.P. Glina, P.M.V. Castro, G.G.R. Monteiro, G.C. Del Guerra, S. Glina, M. Mazzurana, W.M. Bernardo   +6 more
doaj   +1 more source

Co-Crystallization Adducts of Carvedilol with Carboxylic Acids: Design and Characterization

Proceedings
Carvedilol (CARV) belongs to the group of non-selective beta and alpha-1 adrenergic receptor antagonists and is indicated for hypertension and chronic heart failure [...]
Ema-Teodora Nițu, Luciana Buliga, Ioana Mitrofan, Amalia Ridichie, Cornelia Muntean, Ionuţ Ledeţi, Adriana Ledeți, Laura Sbârcea   +7 more
doaj   +1 more source

Does α1-Acid Glycoprotein Act as a Non-functional Receptor for α1-Adrenergic Antagonists?

Journal of Pharmacy and Pharmacology, 1994
AbstractThe ability of a variety of α1-acid glycoproteins (AAG) to affect the intrinsic activity of the α1, -adrenergic antagonist prazosin was studied in rabbit aortic strip preparations. From these studies, the activity of AAG appears to be linked to their ability to bind the antagonist.
M, Qin, S, Oie
openaire   +2 more sources