The Role of BK Potassium Channels in Analgesia Produced by Alpha-2 Adrenergic Receptors [PDF]
BACKGROUND AND OBJECTIVE: Millions of people suffer from pain worldwide, and annually, great economic costs are imposed on societies for pain relief. Analgesics such as alpha-2 adrenergic receptor agonists, which have low risk of complications, can be ...
E Hooshmand +2 more
doaj +3 more sources
Total intravenous anesthesia with propofol, ketamine, and lidocaine associated with dexmedetomidine or xylazine for ovariohysterectomy surgery in female dogs [PDF]
: This study compared cardiovascular and respiratory effects of dexmedetomidine and xylazine in total intravenous anesthesia with propofol, ketamine, and lidocaine.
Gustavo Antônio Boff +4 more
doaj +1 more source
Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats [PDF]
Background Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor.
Dong Joon Kim +5 more
doaj +1 more source
The Role of Alpha-2 Agonists for Attention Deficit Hyperactivity Disorder in Children: A Review
Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which is marked by symptoms such as ...
Elisa E. Neuchat +8 more
doaj +1 more source
Cognitive Function and Urologic Medications for Lower Urinary Tract Symptoms [PDF]
Special considerations should be made when selecting medications for the treatment of lower urinary tract symptoms (LUTS) in older patients especially those over 65 years old.
Yeon Joo Kim, Bum Sik Tae, Jae Hyun Bae
doaj +1 more source
β2-adrenergic agonists modulate TNF-α induced astrocytic inflammatory gene expression and brain inflammatory cell populations [PDF]
Background: The NF-kappa B signaling pathway orchestrates many of the intricate aspects of neuroinflammation. Astrocytic beta(2)-adrenergic receptors have emerged as potential regulators in central nervous system inflammation and are potential targets ...
Aerts, Joeri L +5 more
core +3 more sources
Background Past studies have demonstrated that goal-directed fluid therapy (GDFT) may be more marginal than previously believed. However, beneficial effects of alpha-1 adrenergic agonists combined with appropriate fluid administration is getting more and
Shuai Feng +5 more
doaj +1 more source
Effects of catecholamines on volemic replacement with saline solution and the impact on heart rate variability in rabbits subjected to hemorrhage. A study by spectral analysis [PDF]
PURPOSE: To verify the effects of different catecholamines on volemic expansion and on the autonomic nervous system in rabbits that were subjected to hemorrhage.METHODS: Twenty four rabbits subjected to hemorrhage (with a 25% loss of blood volume) and ...
José Mariano Soares de Moraes +9 more
doaj +1 more source
The effects of six different α-agonists: methoxamine (MET), phenylephrine (PHE), metaraminol (MTA), naphazoline (NAP), oxymetazoline (OXY), and clonidine (CLO), each administered at a dose of 8mg/kg, on the secretion of glycoprotein (GP) and fluid from the submandibular glands were studied in anesthetized rats. Salivation elicited by the drugs occurred
Chihiro Aoki +2 more
openaire +3 more sources
Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J. +5 more
core +1 more source

