Results 21 to 30 of about 42,122 (278)
Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats [PDF]
Anesthesia and Pain Medicine, 2020 Background Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor.
Dong Joon Kim +5 more
doaj +1 more source
The Role of Alpha-2 Agonists for Attention Deficit Hyperactivity Disorder in Children: A Review
Neurology International, 2023 Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which is marked by symptoms such as ...
Elisa E. Neuchat +8 more
doaj +1 more source
Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection [PDF]
Elife 10 (2021): e61700, 2020 In severe viral pneumonia, including Coronavirus disease 2019 (COVID-19), the viral replication phase is often followed by hyperinflammation, which can lead to acute respiratory distress syndrome, multi-organ failure, and death. We previously demonstrated that alpha-1 adrenergic receptor ($\alpha_1$-AR) antagonists can prevent hyperinflammation and ...
arxiv +1 more source
Cognitive Function and Urologic Medications for Lower Urinary Tract Symptoms [PDF]
International Neurourology Journal, 2020 Special considerations should be made when selecting medications for the treatment of lower urinary tract symptoms (LUTS) in older patients especially those over 65 years old.
Yeon Joo Kim, Bum Sik Tae, Jae Hyun Bae
doaj +1 more source
Effects of catecholamines on volemic replacement with saline solution and the impact on heart rate variability in rabbits subjected to hemorrhage. A study by spectral analysis [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE: To verify the effects of different catecholamines on volemic expansion and on the autonomic nervous system in rabbits that were subjected to hemorrhage.METHODS: Twenty four rabbits subjected to hemorrhage (with a 25% loss of blood volume) and ...
José Mariano Soares de Moraes +9 more
doaj +1 more source
BMC Anesthesiology, 2018 Background Past studies have demonstrated that goal-directed fluid therapy (GDFT) may be more marginal than previously believed. However, beneficial effects of alpha-1 adrenergic agonists combined with appropriate fluid administration is getting more and
Shuai Feng +5 more
doaj +1 more source
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source
Dexmedetomidine: present and future directions [PDF]
Korean Journal of Anesthesiology, 2019 Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
doaj +1 more source
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Indian Journal of Ophthalmology, 2015 Aim: To determine the effect of alpha-2-agonist (AA) premedication (PM) on intraocular pressure (IOP) following selective laser trabeculoplasty (SLT).
Julius T Oatts +2 more
doaj +1 more source