Results 101 to 110 of about 93,467 (314)

Antinociceptive Action of Moringa peregrina is Mediated by an Interaction with α2-Adrenergic Receptor

Balkan Medical Journal, 2020
Background: Moringa peregrina (M. peregrina) is an edible, drought-resistant tree that is native to semi-arid countries. It is used as a painkiller in folk medicine. Aims: To study the antinociceptive effects of the leaf extract of M. peregrina in mice.
Sahar M. Jaffal, Belal O. Al-Najjar, Manal A. Abbas, Sawsan A. Oran   +3 more
doaj   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Efficacy and safety of silodosin in the treatment of lower urinary tract symptoms in elderly men taking antihypertensive medications

Prostate International, 2017
Background: Both hypertension and lower urinary tract symptoms (LUTS) are common conditions in the elderly population. This study investigated the efficacy and safety of silodosin in the treatment of LUTS in elderly men who were taking antihypertensive ...
Woo Suk Choi, Min Chul Cho, Jeong Woo Lee, Sang Hoon Song, Jin Kyu Oh, Sang Wook Lee, Sung Yong Cho, Jae Young Park   +7 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Prophylactic effects of alpha-blockers, Tamsulosin and Alfuzosin, on postoperative urinary retention in male patients undergoing urologic surgery under spinal anaesthesia

International Brazilian Journal of Urology, 2016
Purpose Postoperative urinary retention (POUR) is one of the most common complications after surgical procedures under spinal anaesthesia. Recent studies have shown the beneficial effects of alpha-adrenergic blockers in preventing POUR.
Ali Akkoc, Cemil Aydin, Ramazan Topaktas, Mahir Kartalmis, Selcuk Altin, Kenan Isen, Ahmet Metin   +6 more
doaj   +1 more source

Pharmacologic pupil dilation as a predictive test for the risk for intraoperative floppy-iris syndrome [PDF]

, 2011
PURPOSE: To evaluate the effect of α1-adrenergic receptor antagonists (α1-ARAs) on pupil diameter and determine whether the diameter predicts intraoperative floppy-iris syndrome (IFIS).
CASUCCIO, Alessandra, CILLINO, Giovanni, CILLINO, Salvatore, PAVONE, Carlo, SPITALE, Emanuela Rosaria   +4 more
core   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Current and prospective pharmacological targets in relation to antimigraine action [PDF]

, 2008
Migraine is a recurrent incapacitating neurovascular disorder characterized by unilateral and throbbing headaches associated with photophobia, phonophobia, nausea, and vomiting. Current specific drugs used in the acute treatment of migraine interact with
A Bergerot, A Buchwalder, A Carlsson, A Carlsson, A Hughes, A MaassenVanDenBrink, A MaassenVanDenBrink, A May, A May, A May, A Pindon, A Rouleau, A Srikiatkhachorn, A Sudilovsky, A Tanoue, A Wackenfors, AC Honey, AD Bennett, AD Medhurst, AD Michel, AE Luebke, AH Bom, AH Calhoun, AJ Kaumann, AL Magos, AM Aloisi, AM Carruthers, AM Lands, AM Maagdenberg van den, Antoinette MaassenVanDenBrink, AP Ford, AP Silva, B Forssman, B Gómez-Mancilla, B Pouzet, B Schaerlinger, B Weiss, BB Fredholm, BB Hoffman, BJ Francken, BK Kobilka, BK Rasmussen, BW Somerville, BW Somerville, C Hofmann, C Hohoff, C Lampl, C Tzourio, CA Salvatore, Carlos M. Villalón, CG Dahlöf, CM Villalón, CM Villalón, CM Villalón, CM Villalón, CN Sang, CY Yu, D Centurión, D Hoyer, D Hoyer, D Sarsero, DA Curran, David Centurión, DB Bylund, DB Bylund, DB Bylund, DB Bylund, DB Bylund, DD Mitsikostas, DD Mitsikostas, DE Dluzen, DJ Goldstein, DJ Goldstein, DJ Goldstein, DL Jackson, DM Pérez, DR Poyner, DR Thomas, DR Thomas, DS Millson, DW Dodick, E Del Bene, E Enmark, E Fabbretti, E Fusayasu, E Tronvik, EA Barnard, EA MacGregor, EA MacGregor, EA MacGregor, EA MacGregor, EM Cassidy, EW Willems, EW Willems, EW Willems, EW Willems, F Facchinetti, F Facchinetti, F Marceau, F Martínez, FG Freitag, FM Cutrer, FM Cutrer, FM Cutrer, G Attali, G Burnstock, G D’Andrea, G Trapani Di, GA Lambert, GA Michelotti, GL Stiles, GM Terwindt, GW Price, GW Smith, H Doods, H Heyck, H Kaube, H Kowa, H Schrader, HC Diener, HM Vargas, HO Kalkman, HS Blaxall, I Jansen-Olesen, I Mody, IH Page, IT Forbes, J Galitzky, J Honkaniemi, J Olesen, J Olesen, JA Charles, JA Terrón, JB Becker, JC Jen, JC Shih, JD Carroll, JD Classey, JE Palmer, JJ Fernández-Ruíz, JL Brandes, JM Brundege, JM Cruickshank, JM Orshal, JP Dreier, JP Hieble, JP Hieble, JR Arch, JR Clements, JR Docherty, JR Fozard, JW Lomasney, JW Regan, K Kapoor, K Schmuck, K Zimmermann, KA Krobert, KA Petersen, KA Petersen, Kayi Y. Chan, KI Roon, KJ Powell, KL Hoskin, KMA Welch, KP Lesch, KR Oliver, KW Johnson, L Edvinsson, L Edvinsson, L Hein, LA Phebus, LE Limbird, LH Lassen, LH Lassen, LH Lassen, LJ Smith, LL Ven van de, LM McLatchie, M Anthony, M Anthony, M Boccuni, M Cyr, M Farkkila, M Gasparo De, M Hasselblatt, M Iovino, M Kallela, M Mochi, M Oshita, M Peeters, M Quartu, M Spedding, M Yanagisawa, MA Moskowitz, MA Moskowitz, MD Ferrari, MD Ferrari, ME Bigal, ME Erdal, ME Moreau, MG Garry, MG Hanna, MJ Kelly, ML Hernández, MM Rapport, MT Piascik, NG Bowery, NJ Colson, NJ Colson, NJ Giffin, NM Barnes, NM Ramadan, NM Ramadan, NM Ramadan, NT Mathew, O Blin, P Barbanti, P Barbanti, P Geppetti, P Kastner, P Roffey, P Sarchielli, P Sarchielli, P Tfelt-Hansen, P Tfelt-Hansen, P Vries De, P Vries De, PD Drummond, PD Drummond, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PL Durham, PP Lakhlani, PR Saxena, PR Saxena, PR Saxena, PR Saxena, Pramod R. Saxena, PT Hurley, QP Ma, R Burstein, R Cerbo, R Hering-Hanit, R Lodi, R Quirion, R Rabkin, R Uddman, R Würz, RA Bond, RA Ophoff, RB Lipton, RB McCall, RE Widdop, RJ Storer, RJ Storer, RJ Storer, RL Weinshank, RO Millán-Guerrero, RO Millán-Guerrero, RP Ahlquist, RW Kimball, RWM Broek van den, S Akerman, S Akerman, S Akerman, S Akerman, S Akerman, S Cotecchia, S Ghelardoni, S Gupta, S Gupta, S Gupta, S Maude, S Mehrotra, S Mehrotra, S Nag, S Paterna, S Shepheard, S Stellar, Saurabh Gupta, SD Brain, SD Silberstein, SD Silberstein, SD Silberstein, SG Hamilton, SJ Hill, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Tallaksen-Greene, SJ Tepper, SM Lanier, SP Alexander, SP Cook, SP Cook, ST Lee, Suneet Mehrotra, T Attina, T Ishida, T Ishida, T Matsubara, T Takenaka, TJ Murphy, TM Buchanan, TW Ho, U Arulmani, U Arulmani, U Arulmani, V Erspamer, V Erspamer, V Johannsson, V Limmroth, V Shaygannejad, V Simonneaux, VT Martin, W Chai, WF Stewart, WI Bender, WL Hasler, WM Herrmann, WS Lee, Y Dumont, Y Sahara, Y Zhang, YT Lau, Z Cohen, Z Zhang   +335 more
core   +5 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source