Results 171 to 180 of about 989,789 (251)

The nuclear receptor ROR-alpha is a putative novel myogenic regulator of the cardiomyocyte transcriptome, including the alpha-1A adrenergic receptor. [PDF]

Am J Physiol Heart Circ Physiol
Nagalingam RS, Beak JY, Lutze RD, Huang W, Akkina D, Kang C, Zhao A, Alcira BG, Aghajanian A, Gerrish KE, Kang HS, Jetten AM, Jensen BC.   +12 more
europepmc   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Response of human iPSC-cardiomyocytes to adrenergic drugs assessed by high-throughput pericellular oxygen measurements and computational modeling. [PDF]

J Mol Cell Cardiol Plus
Li W, Forouzandehmehr MA, McLeod D, Pozo MR, Heinson YW, Kay MW, Li Z, Morotti S, Entcheva E.   +8 more
europepmc   +1 more source

TMEM16A Ca2+‐activated Cl− channel: Functional interactions with cytoskeletal and membrane‐associated proteins

The Journal of Physiology, EarlyView.
Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura, Rubii Kondo, Yoshiaki Suzuki, Yuji Imaizumi, Aya Yamamura   +4 more
wiley   +1 more source

The use of Silodosin in Ureterolithiasis is the Hot Topic in this Number of International Brazilian Journal of Urology. [PDF]

Int Braz J Urol
Favorito LA.
europepmc   +1 more source

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Reduction in Wearable-Derived Maximal Oxygen Consumption (VO₂max) During Tamsulosin Use in an Endurance Athlete. [PDF]

Cureus
Cohn H, Zamani A, Sessine M, Cher ML.
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Intranasal dexmedetomidine for perioperative analgesia in a patient on naltrexone maintenance therapy. [PDF]

Indian J Anaesth
Rangari A, Singh S, Mittal S, Garg H.
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source