Results 211 to 220 of about 36,879 (305)

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease

open access: yesExperimental Physiology, EarlyView.
Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka   +3 more
wiley   +1 more source

Cocoa shell extract supplementation in hypertensive rats induces outward hypertrophic remodelling in mesenteric resistance arteries, reducing fibrosis

open access: yesExperimental Physiology, EarlyView.
Abstract Hypertension is the leading risk factor for cardiovascular diseases and is difficult to control, putting the focus on foods and nutraceuticals. Cocoa has beneficial cardiovascular effects but generates large amounts of residues, such as cocoa shells, which contain bioactive molecules.
Pilar Rodríguez‐Rodríguez   +7 more
wiley   +1 more source

α1D Adrenergic Receptor Antagonism Protects Against High Glucose-Induced Mitochondrial Dysfunction and Blood Retinal Barrier Breakdown in ARPE-19 Cells. [PDF]

open access: yesInt J Mol Sci
Giuffrida E   +9 more
europepmc   +1 more source

Ageing exacerbates the adverse effects of respiratory muscle fatigue on vascular function, locomotor muscle fatigue and exercise performance in males

open access: yesExperimental Physiology, EarlyView.
Abstract This study investigated the effect of respiratory muscle fatigue on cardiovascular function, locomotor muscle fatigue and exercise performance in young and master athletes, a model of successful ageing. Ten young male (YA, 27.4 ± 4.4 years) and 11 male master endurance athletes (MA, 65.0 ± 5.1 years) performed, on separate days, two constant ...
Valentin Mons   +4 more
wiley   +1 more source

Phentolamine Infusion for the Treatment of Norepinephrine Extravasation in a Dog. [PDF]

open access: yesJ Vet Emerg Crit Care (San Antonio)
Flynn GE   +3 more
europepmc   +1 more source

Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa   +7 more
wiley   +1 more source

Asp125 and Thr130 in Transmembrane Domain 3 Are Major Sites of .ALPHA.1b-Adrenergic Receptor Antagonist Binding

open access: bronze, 2007
Kazuya Takahashi   +5 more
openalex   +2 more sources

Exploring neuronal mechanisms of osteosarcopenia in older adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

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