Results 231 to 240 of about 36,879 (305)

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

open access: yesMedicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni   +5 more
wiley   +1 more source

Neurotransmitter signaling in white matter [PDF]

open access: yes, 2014
Butt, Arthur M.   +2 more
core   +1 more source

The Effects of Dexmedetomidine on Postoperative Delirium in Adult Cardiac Surgical Patients: A Bayesian Meta‐Analysis and Trial Sequential Analysis

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Background An acute episode of delirium among adults following cardiac surgery is associated with increased length of stay in intensive care, prolonged mechanical ventilation, and increased risk of mortality. This robust systematic review with Bayesian meta‐analysis, including trial sequential analysis, has been undertaken to explore the use ...
Naomi Keith   +4 more
wiley   +1 more source

Therapeutic Targeting of the α7 Nicotinic Receptor: Challenges and Prospects for Cognitive Improvement in Alzheimer's and Schizophrenia

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.
ABSTRACT The α7 nicotinic acetylcholine receptor (α7 nAChR) has emerged as a key target for treating cognitive dysfunction in neurological disorders such as Alzheimer's disease (AD) and schizophrenia. α7 nAChRs play essential roles in neurotransmission, neuroinflammation and synaptic plasticity, not only in neurons but also in glial cells, where they ...
Janus H. Magnussen
wiley   +1 more source

Association Between Alpha-1 Adrenoreceptor Antagonist Use and Cognitive Impairment: A Systematic Review. [PDF]

open access: yesInt Neurourol J
Kingsley R   +7 more
europepmc   +1 more source

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