Results 231 to 240 of about 93,467 (314)

Vasospastic angina: Pathophysiology, diagnosis, and emerging therapeutic approaches. [PDF]

World J Cardiol
Ralota KK, Layland J.
europepmc   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

Experimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson, Man Si, Krystle Trosclair, Ellen Aughenbaugh, Maxine Parkinson, Nicole M. Gautier‐Hall, Megan Watts, Frederica Kizek, Md. Shenuarin Bhuiyan, Paari Dominic, Kathryn A. Hamilton, Edward Glasscock   +11 more
wiley   +1 more source

Thermogenic Targets for Obesity Management in the Era of Incretin-Based Therapies. [PDF]

Pharmaceuticals (Basel)
Soliman S, Andrews-Dickert R, Rocic P, Mitov M.   +3 more
europepmc   +1 more source

Exploring neuronal mechanisms of osteosarcopenia in older adults

The Journal of Physiology, EarlyView.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

Role of TRPV1 in neuroendocrine regulation: a potential target against obesity? [PDF]

Front Immunol
Wang J, Liu M, Wen L, Xing P, Chen J, Xia X, Ding W.   +6 more
europepmc   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Autonomic nervous system dysfunction in chronic obstructive pulmonary disease: mechanistic insights and therapeutic implications. [PDF]

Ann Med
Chen D, Zhou Z, Zhou Z, Zhao L, Chen Y.
europepmc   +1 more source

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

The Journal of Physiology, EarlyView.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus, Praveen Kumar, Kelly Kneale, T. Noah Hutson, Nicole M. Gautier‐Hall, Deng‐Shan Shiau, Megan Watts, Krystle Trosclair, Hemangini A. Dhaibar, Paari Dominic, Leonidas Iasemidis, Edward Glasscock   +11 more
wiley   +1 more source

Unexpected Paraganglioma Identified During Bilateral Nephrectomy in Autosomal Dominant Polycystic Kidney Disease: A Case Report. [PDF]

Cureus
Vollet M, Blanc C, Matter M, Hofmann G.
europepmc   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source