Results 21 to 30 of about 989,789 (251)

A Prospective, Multicenter, Open-Label Study of Dose Escalation Therapy in Male Patients With Nocturia Refractory to 0.2-mg Tamsulosin Monotherapy [PDF]

International Neurourology Journal, 2019
Purpose To investigate the efficacy and safety of 0.4 mg of tamsulosin in patients with nocturia not responding to 0.2 mg. Methods Patients with intractable nocturia after treatment with 0.2 mg of tamsulosin for>1 month were included in a multicenter ...
Ho Song Yu, Jeong Woo Lee, Jihyeong Yu, Min Chul Cho, Sung Yong Cho   +4 more
doaj   +1 more source

The use of α1-adrenergic receptor antagonists in the prevention of adverse outcomes of COVID-19 infection in obese patients

Advances in Human Biology, 2022
Obesity is widely reported to be associated with a higher risk of the severity and worse clinical outcome of COVID-19. With the global prevalence of obesity, exploring the relationship between obesity and the severity of COVID-19 disease is of major ...
Auda Fares, Resul Toprak, Dieter Borrman, Julius R Ivester   +3 more
doaj   +1 more source

The Noradrenergic System is Partly Involved in Resveratrol Antidepressant and Anti-Obsessive Like Effects in Mice Model [PDF]

Research Journal of Pharmacognosy, 2021
Background and objectives: Resveratrol is a natural phenol in food particularly the skin of fruits like red grapes. It has shown biological, and antidepressant effects.
Azadeh Mesripour*, Fatemeh Payandekhah
doaj   +1 more source

Cognitive Function and Urologic Medications for Lower Urinary Tract Symptoms [PDF]

International Neurourology Journal, 2020
Special considerations should be made when selecting medications for the treatment of lower urinary tract symptoms (LUTS) in older patients especially those over 65 years old.
Yeon Joo Kim, Bum Sik Tae, Jae Hyun Bae
doaj   +1 more source

The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19

Frontiers in Medicine, 2021
Effective therapies for coronavirus disease 2019 (COVID-19) are urgently needed, and pre-clinical data suggest alpha-1 adrenergic receptor antagonists (α1-AR antagonists) may be effective in reducing mortality related to hyperinflammation independent of ...
Liam Rose, Laura Graham, Allison Koenecke, Michael Powell, Ruoxuan Xiong, Zhu Shen, Brett Mench, Kenneth W. Kinzler, Chetan Bettegowda, Chetan Bettegowda, Bert Vogelstein, Susan Athey, Joshua T. Vogelstein, Joshua T. Vogelstein, Maximilian F. Konig, Maximilian F. Konig, Todd H. Wagner, Todd H. Wagner   +17 more
doaj   +1 more source

The Effectiveness of Silodosin for Nocturnal Polyuria in Elderly Men With Benign Prostatic Hyperplasia: A Multicenter Study [PDF]

International Neurourology Journal, 2015
Purpose: To investigate improvement in nocturia and nocturnal polyuria in nocturnal polyuria patients after silodosin administration by using a 3-day frequency volume chart. Methods: This was a prospective multicenter study.
Young Won Kim, Jinsung Park, Hong Chung, Hong-Wook Kim, Hyung Joon Kim, Jae Hung Jung, Won Tae Kim   +6 more
doaj   +1 more source

Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling [PDF]

, 2014
Grazia Daniela Femminella,1 Vincenzo Barrese,2,3 Nicola Ferrara,1,4 Giuseppe Rengo4 1Department of Translational Medical Sciences, Federico II University, Naples, Italy; 2Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II
Ferrara, N, Barrese V, Ferrara N, FERRARA, NICOLA, Rengo, G, Barrese, Vincenzo, FEMMINELLA, GRAZIA DANIELA, Femminella GD, Barrese, V, Rengo G, Femminella, GD, RENGO, GIUSEPPE   +11 more
core   +1 more source

Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate [PDF]

, 2011
Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction.
Goettinger, Johanna, Martin Hennenberg, Christian G. Stief, Petter Hedlund, Göttinger, Johanna,, Stief, Christian G., Christian Gratzke, Andersson, Karl-Erik, Reich, Oliver,, Reich, Oliver, Johanna Göttinger, Stief, Christian G.,, Schlenker, Boris,, Bauer, Ricarda M.,, Hedlund, Petter,, Andersson, Karl-Erik,, Strittmatter, Frank, Hennenberg, Martin,, Bauer, Ricarda M., Oliver Reich, Gratzke, Christian,, Ricarda M. Bauer, Hedlund, Petter, Frank Strittmatter, Karl-Erik Andersson, Gratzke, Christian, Hennenberg, Martin, Strittmatter, Frank,, Schlenker, Boris, Boris Schlenker   +29 more
core   +1 more source

Inhibition of the lipolytic action of beta-adrenergic agonists in human adipocytes by alpha-adrenergic agonists.

Journal of Lipid Research, 1981
The aim of this study was to define the role of the alpha-adrenergic receptor in the regulation of lipolysis by human adipocytes. Glycerol production by isolated human adipocytes was stimulated by the pure beta-adrenergic agonist isoproterenol in a dose ...
E E Wright, E R Simpson
doaj   +1 more source

Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle. [PDF]

, 2012
The transcription factors Elk1 and serum response factor (SRF) are central regulators of cell cycle and phenotype in various cell types. Elk1 is activated by phosphorylation (serine-383), while activation of SRF requires its co-factor, myocardin ...
Christian G Stief, Strittmatter, Frank, Martin Hennenberg, Waidelich, Raphaela, Beckmann, Christer, Füllhase, Claudius, Rutz, Beata, Montorsi, Francesco, Petter Hedlund, Christer Beckmann, Christian Gratzke, Stief, Christian Georg, Raphaela Waidelich, Hedlund, Petter, Frank Strittmatter, Karl-Erik Andersson, Andersson, Karl-Erik, Francesco Montorsi, Hennenberg, Martin, Gratzke, Christian, Beata Rutz, Claudius Füllhase   +21 more
core   +1 more source