Results 121 to 130 of about 42,003 (148)

β-Adrenergic Signaling Contributes to Circadian and Lipid Dysregulation in Meibomian Glands During Chronic Psychological Stress. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Qi D   +11 more
europepmc   +1 more source

Interactions of putatively irreversible antagonists with β1− and β2− adrenergic receptors

Biochemical Pharmacology, 1986
Three compounds that have been suggested to irreversibly inactivate beta-adrenergic receptors were studied: NHNPNBE [N-(2-hydroxy-3-[1-napthoxy]-propyl)-N-bromoacetylethylenediami ne], BAAM (bromoacetylalprenololmenthane), and Ro 3-7894 [1-(5-chloracetylaminobenzfuran-2-yl)-2-isopropylaminoethanol++ +].
K P, Minneman, C B, Mowry
openaire   +2 more sources

Bucindolol, a Nonselective β1- and β2-Adrenergic Receptor Antagonist, Decreases β-Adrenergic Receptor Density in Cultured Embryonic Chick Cardiac Myocyte Membranes

Journal of Cardiovascular Pharmacology, 2001
Bucindolol and carvedilol, nonselective beta1- and beta2-adrenergic receptor antagonists, have been widely used in clinical therapeutic trials of congestive heart failure. The aim of the current study was to investigate long-term effects of bucindolol or carvedilol on beta-adrenergic receptor protein and gene expression in cardiac myocytes.
K, Asano   +5 more
openaire   +2 more sources

Coexistence of beta-1 and beta-2 adrenergic receptors in the human heart: effects of treatment with receptor antagonists or calcium entry blockers.

The Journal of Pharmacology and Experimental Therapeutics, 1985
The properties of the binding of [125I]iodopindolol ([125I]IPIN) to beta adrenergic receptors on plasma membranes prepared from right atrial tissue removed during cardiac bypass surgery were investigated. Some of the patients from whom the tissue was removed had been treated before surgery with either a beta adrenergic receptor antagonist or a calcium ...
A, Hedberg   +3 more
openaire   +2 more sources

Abstract 641: Renal Denervation does not Lower Blood Pressure in Spontaneously Hypertensive Rats Treated with a Beta-1 Adrenergic Receptor Antagonist.

Hypertension, 2014
We have used the SHR as an animal model to understand how renal denervation (RDN) lowers blood pressure. In order to determine how concomitant antihypertensive drug therapy could affect the blood pressure response to RDN, we performed RDN both before and after chronic (several days) treatment via the drinking water with the selective alpha-1 adrenergic
Jeremiah Phelps, Gregory Fink
openaire   +1 more source

Nebivolol: a selective β1-adrenergic receptor antagonist that relaxes vascular smooth muscle by nitric oxide- and cyclic GMP-dependent mechanisms

Nitric Oxide, 2002
Nebivolol is a highly selective beta(1)-adrenergic receptor antagonist that also possesses vasodilator properties that are attributed largely to nitric oxide (NO). The objective of the present study was to elucidate in more detail the mechanisms by which nebivolol relaxes vascular smooth muscle.
Louis J, Ignarro   +4 more
openaire   +2 more sources

[The effects of combined beta(1) adrenergic receptor antagonist and beta(2) adrenergic receptor agonist therapy on cardiac function and myocardial apoptosis in heart failure rats].

Zhonghua xin xue guan bing za zhi, 2009
To observe the effects of combined beta(1) adrenergic receptor (AR) antagonist with beta(2)AR agonist therapy on cardiac function and cardiomyocyte apoptosis in heart failure rats.Heart failure was induced by isoproterenol and rats were randomly divided into metoprolol group (50 mg/kg twice daily/gavage, n = 11), combined treatment group (fenoterol 125
Wei-min, Li   +5 more
openaire   +1 more source

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