Results 51 to 60 of about 42,003 (148)

Heteroreceptor complexes and their allosteric receptor-receptor interactions in the central nervous system. Focus on examples from Dopamine D2 and Serotonin 5-HT1a receptors [PDF]

open access: yes, 2018
GPCR interacting proteins (specially β- arrestin) and their receptor-protein interactions are also covered but their interactions with the allosteric receptor-receptor interactions in heteroreceptor complexes remain to be elucidated.
Corrales Ferro, Fidel
core   +1 more source

Glycyrrhizic Acid Reduces Heart Rate and Blood Pressure by a Dual Mechanism [PDF]

open access: yes, 2016
published_or_final_versio
Chow, BKC, Sekar, R, SINGH, K, ZAW, AM
core   +1 more source

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome [PDF]

open access: yes, 2008
Background: Progressive enlargement of the aortic root, leading to dissection, is the main cause of premature death in patients with Marfan's syndrome. Recent data from mouse models of Marfan's syndrome suggest that aortic-root enlargement is caused by ...
Brooke, Benjamin S.   +5 more
core   +2 more sources

Postnatal β2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle [PDF]

open access: yes, 2019
Placental insufficiency causes intrauterine growth restriction (IUGR) and disturbances in glucose homeostasis with associated β adrenergic receptor (ADRβ) desensitization.
Allen, Ronald E.   +11 more
core   +1 more source

Considering the role of Murine double minute 2 in the cardiovascular system [PDF]

open access: yes, 2019
The E3 ubiquitin ligase Murine double minute 2 (MDM2) is the main negative regulator of the tumor protein p53 (TP53). Extensive studies over more than two decades have confirmed MDM2 oncogenic role through mechanisms both TP53-dependent and TP53 ...
Lam, Brian, Roudier, Emile
core   +1 more source

The future of pharmacogenetics in the treatment of heart failure [PDF]

open access: yes, 2015
Heart failure is a common disease with high levels of morbidity and mortality. Current treatment comprises β-blockers, ACE inhibitors, aldosterone antagonists and diuretics.
Alex S Doney   +11 more
core   +2 more sources

Profile of sacubitril/valsartan in the treatment of heart failure: patient selection and perspectives

open access: yesVascular Health and Risk Management, 2017
Srikanth Yandrapalli,1 Gabriela Andries,1 Medha Biswas,2 Sahil Khera2,3 1Department of Internal Medicine, New York Medical College at Westchester Medical Center, Valhalla, NY, USA; 2Division of Cardiology, New York Medical College at Westchester Medical ...
Yandrapalli S   +3 more
doaj  

Stress-Dependent Impairment Of Passive-Avoidance Memory By Propranolol Or Naloxone [PDF]

open access: yes, 2011
Previous work has shown that the effect of opioid-receptor blockade on memory modulation is critically dependent upon the intensity of stress. The current study determined the effect of adrenergic-receptor blockade on memory modulation under varied ...
Atapattu, Ranga Keshani, , \u2708   +3 more
core   +2 more sources

Triple therapy (ICS/LABA/LAMA) in COPD: time for a reappraisal

open access: yesInternational Journal of COPD, 2018
Lowie Vanfleteren,1–3 Leonardo M Fabbri,1,4 Alberto Papi,4 Stefano Petruzzelli,5 Bartolome Celli6 1COPD Center, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden; 2CIRO, Horn, the Netherlands ...
Vanfleteren L   +4 more
doaj  

Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]

open access: yes, 2014
Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A   +7 more
core   +2 more sources

Home - About - Disclaimer - Privacy